Wang Ziye, Zhao Shiqing, Zhong Xiaotian, Su Yi, Song Yahan, Li Jun, Shi Yanyan
Research Center of Clinical Epidemiology, Peking University Third Hospital, Beijing, China.
Peking University Health Science Center, Beijing, China.
Front Microbiol. 2024 Nov 6;15:1479941. doi: 10.3389/fmicb.2024.1479941. eCollection 2024.
BACKGROUND: Inflammatory bowel diseases (IBD) are chronic inflammation conditions affecting the gastrointestinal tract. Studies point out an association between () infection and IBD. This study aims to visually assess the research trends and hotspots in the field of infection and IBD, review mainstream perspectives in this field, and provide a foundation for future research and treatment. METHODS: We searched the Web of Science Core Collection Database for literature related to and IBD, using VOS viewer to generate visual charts. RESULTS: A total of 246 publications were included, with articles being the predominant type of document. A significant increase in the number of publications was observed after 2011. China contributed the most of researches. Keyword clusters revealed that the researches primarily focused on immune mechanism, gut microbiome, diagnosis and treatment of IBD. Time trend results indicated that current researches centered on gut microbiota and immune mechanisms. CONCLUSION: infection may have a protective effect on IBD. The exact mechanisms remain unclear and may involve immunomodulation and changes of gut microbiota. Further researches are necessary for better understanding this relationship and its implications for clinical practice. Further researches and clinical practice should pay attention to this topic.
背景:炎症性肠病(IBD)是影响胃肠道的慢性炎症性疾病。研究指出()感染与IBD之间存在关联。本研究旨在直观评估()感染与IBD领域的研究趋势和热点,综述该领域的主流观点,并为未来的研究和治疗提供基础。 方法:我们在科学网核心合集数据库中搜索与()和IBD相关的文献,使用VOSviewer生成可视化图表。 结果:共纳入246篇出版物,其中文章是主要的文献类型。2011年后出版物数量显著增加。中国的研究贡献最多。关键词聚类显示,研究主要集中在IBD的免疫机制、肠道微生物群、诊断和治疗。时间趋势结果表明,当前的研究集中在肠道微生物群和免疫机制上。 结论:()感染可能对IBD有保护作用。确切机制尚不清楚,可能涉及免疫调节和肠道微生物群的变化。为了更好地理解这种关系及其对临床实践的影响,有必要进行进一步的研究。进一步的研究和临床实践应关注这一主题。
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