Wang Wei, Gao Yamin, Ji Jianyu, Huang Zhai, Xiong Bin, Xiang Shulin
Department of Intensive Care Unit, The Peoples Hospital of Guangxi Zhuang Autonomous Region, Nanning, Guangxi, China.
Research Center of Communicable and Severe Diseases, Guangxi Academy of Medical Sciences, Nanning, Guangxi, China.
Front Microbiol. 2025 Jan 8;15:1514738. doi: 10.3389/fmicb.2024.1514738. eCollection 2024.
Leptospirosis is an acute zoonotic disease caused by pathogenic , primarily transmitted to humans through contact with water or soil contaminated by the bacteria. It is globally distributed, with heightened prevalence in tropical regions. While prior studies have examined the pathophysiology, epidemiology, and risk factors of leptospirosis, few have explored trends and emerging topics in the field. This study applies bibliometric analysis to generate a visual knowledge map, identifying research hotspots and forecasting future trends in leptospirosis investigations.
Data were extracted from the Web of Science Core Collection (WOSCC), encompassing all publications up to May 1, 2024. CiteSpace and VOSViewer software were used to analyze annual publication trends, as well as contributions from countries, institutions, journals, authors, references, and keywords, thereby pinpointing current research priorities and potential future directions.
A total of 5,244 articles were included, sourced from 4,716 institutions, 955 journals, and 156 countries or regions. The United States led with 1,315 publications and had the most significant influence in the field. "PLOS Neglected Tropical Diseases" published the highest number of articles (166), while "Infection and Immunity" garnered the most citations (6,591). Prominent research areas included restriction endonucleases, monoclonal antibodies, outer membrane proteins, water environments, detection methods, and antimicrobial agents. Research focus has shifted from early genomic and antigenic studies to investigations into outer membrane protein functions and environmental persistence, culminating in recent advances in molecular mechanisms and diagnostic technology development.
This bibliometric analysis provides a comprehensive snapshot of leptospirosis research, emphasizing collaborations and impact among authors, countries, institutions, and journals. It offers valuable insights into ongoing trends and serves as a reference for future collaboration and research opportunities in the field.
钩端螺旋体病是一种由致病性钩端螺旋体引起的急性人畜共患病，主要通过接触被该细菌污染的水或土壤传播给人类。它在全球范围内分布，在热带地区发病率更高。虽然先前的研究已经探讨了钩端螺旋体病的病理生理学、流行病学和危险因素，但很少有研究探讨该领域的趋势和新出现的主题。本研究应用文献计量分析来生成一个可视化的知识图谱，识别钩端螺旋体病研究的热点并预测未来趋势。
数据从科学网核心合集（WOSCC）中提取，涵盖截至2024年5月1日的所有出版物。使用CiteSpace和VOSViewer软件分析年度出版趋势，以及国家、机构、期刊、作者、参考文献和关键词的贡献，从而确定当前的研究重点和潜在的未来方向。
共纳入5244篇文章，来自4716个机构、955种期刊以及156个国家或地区。美国以1315篇出版物领先，在该领域具有最大影响力。《公共科学图书馆·被忽视的热带病》发表的文章数量最多（166篇），而《感染与免疫》获得的引用次数最多（6591次）。突出的研究领域包括限制性内切酶、单克隆抗体、外膜蛋白、水环境、检测方法和抗菌剂。研究重点已从早期的基因组和抗原研究转向对外膜蛋白功能和环境持久性的研究，最终在分子机制和诊断技术开发方面取得了最新进展。
这项文献计量分析提供了钩端螺旋体病研究的全面概况，强调了作者、国家、机构和期刊之间的合作与影响。它为当前趋势提供了有价值的见解，并为该领域未来的合作和研究机会提供了参考。
