European Centre for Disease Prevention and Control, Stockholm, Sweden.
Austrian National Reference Centre for Antimicrobial Resistance, Ordensklinikum Linz Elisabethinen, Linz, Austria.
Euro Surveill. 2024 Nov;29(47). doi: 10.2807/1560-7917.ES.2024.29.47.2400727.
Analysis of 594 isolates of sequence type (ST)131 and its single locus variants carrying carbapenemase genes from 17 European Union/European Economic Area countries revealed acquisition of 18 carbapenemase variants, mainly in ST131 clades A and C. Most frequent were (n = 230) and (n = 224), detected in 14 and 12 countries, respectively. Isolates carrying have increased rapidly since 2021. The increasing detection of carbapenemase genes in the high-risk lineage ST131 is a public health concern.
对来自欧盟/欧洲经济区 17 个国家的 594 株携带碳青霉烯酶基因的 131 型序列(ST)及其单一位点变异株进行分析,发现获得了 18 种碳青霉烯酶变异株,主要在 ST131 亚群 A 和 C 中。最常见的是 (n=230) 和 (n=224),分别在 14 个和 12 个国家中检测到。自 2021 年以来,携带 的菌株迅速增加。高产碳青霉烯酶基因的高危谱系 ST131 的检测不断增加,这是一个公共卫生关注的问题。