2019 至 2020 年德国出现携带碳青霉烯酶耐药基因 ST131 的 ……
Emergence of carbapenem-resistant ST131 carrying in Germany, 2019 to 2020.
机构信息
Institute for Medical Microbiology and Hygiene, Medical Faculty Mannheim of Heidelberg University, Mannheim, Germany.
Medical Microbiology and Hygiene, Department of Infectious Diseases, Heidelberg University Hospital, Heidelberg, Germany.
出版信息
Euro Surveill. 2020 Nov;25(46). doi: 10.2807/1560-7917.ES.2020.25.46.2001815.
The dissemination of carbapenem-producing Gram-negative bacteria is a major public health concern. We report the first detection of OXA-244-producing ST131 O16:H5 in three patients from two tertiary hospitals in the south-west of Germany. OXA-244 is emerging in Europe. Because of detection challenges, OXA-244-producing may be under-reported. The emergence of carbapenem resistance in a globally circulating high-risk clone, such as ST131 is of clinical relevance and should be monitored closely.
产碳青霉烯类肠杆菌科细菌的传播是一个主要的公共卫生关注点。我们报告了在德国西南部的两家三级医院的 3 名患者中首次检出产 OXA-244 的 ST131 O16:H5。OXA-244 在欧洲正在出现。由于检测方面的挑战，产 OXA-244 的 可能报告不足。在具有全球传播的高风险克隆（如 ST131）中出现碳青霉烯类耐药性具有临床相关性，应密切监测。
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