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加强公共卫生系统以应对尼帕病毒日益增长的威胁:呼吁全球做好准备并做出应对。

Strengthening Public Health Systems to Combat the Rising Threat of Nipah Virus: A Call for Global Preparedness and Response.

作者信息

Yadav Amisha, Singh Vijay

机构信息

Department of Neurosurgery OT, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Department of Biochemistry, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India.

出版信息

Adv Exp Med Biol. 2025;1476:111-132. doi: 10.1007/5584_2024_836.

Abstract

The chapter explores ways to increase global preparedness as well as reactions to the Nipah virus, which is a devastating zoonotic risk with serious health impacts. The Nipah virus is transmitted through bats and humans and poses major problems due to its high mortality rate, fast spread, and the absence of treatments or vaccines. The chapter argues for a holistic strategy incorporating the One Health framework to address human, animal, and environmental health interdependence. The chapter focuses on key areas to boost readiness, which include creating effective real-time surveillance systems, enhancing medical infrastructure, and accelerating studies on therapeutics and vaccines. The chapter emphasizes the need for efficient risk communication and engagement with the community to control the spread of disease. In addition, the chapter examines the importance of maintaining international health security financing as well as international collaboration to improve the ability to respond and prepare. Through analyzing case studies that have proven successful and policy recommendations, the chapter seeks to offer an outline for the development of robust health systems that are resilient and reduce the effects of the Nipah virus as well as other newly discovered pathogens.

摘要

本章探讨了提高全球防范能力的方法以及对尼帕病毒的应对措施,尼帕病毒是一种具有严重健康影响的毁灭性人畜共患病风险。尼帕病毒通过蝙蝠传播给人类,因其高死亡率、快速传播以及缺乏治疗方法或疫苗而带来重大问题。本章主张采用纳入“同一健康”框架的整体战略,以解决人类、动物和环境健康的相互依存关系。本章重点关注加强防范准备的关键领域,包括建立有效的实时监测系统、加强医疗基础设施以及加速治疗方法和疫苗的研究。本章强调了进行有效风险沟通以及与社区互动以控制疾病传播的必要性。此外,本章审视了维持国际卫生安全融资以及开展国际合作以提高应对和防范能力的重要性。通过分析已证明成功的案例研究和政策建议,本章力求为建立强大、有韧性且能减轻尼帕病毒以及其他新发现病原体影响的卫生系统提供一个发展纲要。

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