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原发性恶性心包间皮瘤多学科治疗的长期生存:一例报告

Long-term survival from multidisciplinary treatment of primary malignant pericardial mesothelioma: A case report.

作者信息

Hai Vu Anh, Chau Nghiem Thi Minh, Hoanh Ho Viet, Van Tri Ha, Pho Dinh Cong, Van Nam Nguyen

机构信息

Oncology Center, Military Hospital 103, Vietnam Military Medical University, Hanoi 10000, Viet Nam.

Department of Cardiology, Heart Institute, 108 Military Central Hospital, Hanoi 100000, Viet Nam.

出版信息

Int J Surg Case Rep. 2024 Dec;125:110615. doi: 10.1016/j.ijscr.2024.110615. Epub 2024 Nov 15.

Abstract

INTRODUCTION AND IMPORTANCE

Primary malignant pericardial mesothelioma is an extremely rare disease with a poor prognosis. Currently, there are no specific guidelines for diagnosis and treatment in Vietnam and international countries for this disease, so treatment experiences from previous clinical cases are very important in the management of this disease.

CASE PRESENTATION

The research team reports a clinical case diagnosed and treated with a combination of surgery and chemotherapy using the Pemetrexed + Carboplatin regimen at the Oncology Center. The patient has survived for an additional 17 months up to the current time.

CLINICAL DISCUSSION

This is an exceptionally rare incident. He survived for a duration of 17 months, which is almost three times longer than the average survival time observed in other documented cases. Additional reports on cases with pericardial mesothelioma are necessary to have a comprehensive understanding of its nature, enabling early identification and appropriate treatment.

CONCLUSION

The patient underwent surgical intervention and received chemotherapy as part of their treatment. The research team emphasizes the importance of a multidisciplinary approach in diagnosing and treating primary malignant pericardial mesothelioma.

摘要

引言与重要性

原发性恶性心包间皮瘤是一种极为罕见的疾病,预后较差。目前,越南及国际上针对该疾病尚无具体的诊断和治疗指南,因此以往临床病例的治疗经验对于该疾病的管理非常重要。

病例介绍

研究团队报告了一例在肿瘤中心采用培美曲塞+卡铂方案联合手术及化疗进行诊断和治疗的临床病例。该患者截至目前已存活17个月。

临床讨论

这是一个极其罕见的病例。他存活了17个月,几乎是其他已记录病例平均存活时间的三倍。需要更多关于心包间皮瘤病例的报告,以便全面了解其性质,实现早期识别和恰当治疗。

结论

该患者接受了手术干预并接受化疗作为治疗的一部分。研究团队强调多学科方法在原发性恶性心包间皮瘤诊断和治疗中的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2e54/11621602/94261bd73c7a/gr1.jpg

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