牙周膜来源的小细胞外囊泡的再生潜力
Regenerative Potential of PDL-Derived Small Extracellular Vesicles.
作者信息
Birjandi Anahid A, Lynham Steven, Matalova Eva, Ghuman Mandeep, Sharpe Paul
机构信息
Centre for Craniofacial and Regenerative Biology, Faculty of Dentistry, Oral & Craniofacial Sciences, Kings College London, London, UK.
Centre of Excellence for Mass Spectrometry, Denmark Hill, King's College London, London, UK.
出版信息
J Periodontal Res. 2025 Apr;60(4):392-394. doi: 10.1111/jre.13356. Epub 2024 Nov 24.
Abstract
Treatment of gingival fibroblasts with PDL extracellular vesicles results in promotion of Wnt signalling pathway and osteogenic differentiation. PDL secretome shows selective wound healing and matrix remodelling which can have implications for future periodontal regenerative strategies.
摘要
用牙周膜细胞外囊泡处理牙龈成纤维细胞可促进Wnt信号通路和骨分化。牙周膜分泌组显示出选择性伤口愈合和基质重塑，这可能对未来的牙周再生策略具有重要意义。
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