Kim Ji-Hun, Lee Rami, Hwang Sung-Hee, Choi Sun-Hye, Kim Jong-Hoon, Cho Ik-Hyun, Lee Jeong Ik, Nah Seung-Yeol
Ginsentology Research Laboratory and Department of Physiology, College of Veterinary Medicine, Konkuk University, Seoul, Republic of Korea.
Department of Pharmaceutical Engineering, College of Health Sciences, Sangji University, Wonju, Republic of Korea.
J Ginseng Res. 2024 Nov;48(6):525-534. doi: 10.1016/j.jgr.2024.09.006. Epub 2024 Sep 25.
Ginseng is a traditional herbal medicine with a long history of use for the prevention and/or treatment of various diseases. Ginseng is used worldwide as a functional food to maintain human health. In addition, ginseng has been used as a raw ingredient in cosmetics with various applications, ranging from skin toning to anti-aging. Some cosmetic products contain ginseng extracts from Korea and other countries, as it is thought that ginseng can also exert beneficial effects on human skin. However, it remains unclear which ginseng component(s) could be the main active compound that directly contributes to skin health and/or prevents skin aging. It is also important to understand the mechanisms by which the ginseng component(s) exert their effects on the skin and skin health. This review describes recent and studies involving ginseng extracts, ginseng ingredients, and ginseng byproducts for skincare and skin health and discusses emerging evidence that ginsenosides, gintonin, and ginseng byproducts could be novel candidates for skincare and skin health applications ranging from anti-aging to the treatment of skin diseases such as atopic dermatitis and hypertrophic scars and keloids. The mechanisms underlying the beneficial effects of ginseng components and byproducts on skin health are discussed. In addition, this review shows how ginseng components, such as gintonin, a newly identified ginseng component, might contribute to skin health and skin disease when used as a supplementary ingredient in cosmetics and further proposes a novel combination in cosmetic products containing both ginsenosides and gintonin.
人参是一种传统草药，长期以来一直用于预防和/或治疗各种疾病。人参在全球范围内被用作功能性食品以维持人体健康。此外，人参还被用作化妆品的原料，具有多种用途，从提亮肤色到抗衰老。一些化妆品含有来自韩国和其他国家的人参提取物，因为人们认为人参对人体皮肤也能产生有益效果。然而，目前尚不清楚人参的哪些成分可能是直接促进皮肤健康和/或预防皮肤衰老的主要活性化合物。了解人参成分对皮肤和皮肤健康产生作用的机制也很重要。这篇综述描述了最近有关人参提取物、人参成分和人参副产品用于护肤和皮肤健康的研究，并讨论了新出现的证据，即人参皂苷、人参炔醇和人参副产品可能是护肤和皮肤健康应用的新候选物，其应用范围从抗衰老到治疗特应性皮炎、增生性瘢痕和瘢痕疙瘩等皮肤疾病。文中讨论了人参成分和副产品对皮肤健康产生有益影响的潜在机制。此外，这篇综述展示了人参成分，如新发现的人参成分人参炔醇，在用作化妆品补充成分时可能如何促进皮肤健康和预防皮肤疾病，并进一步提出了一种同时含有人参皂苷和人参炔醇的化妆品的新型组合。
