Deng Kexin, Liu Yi, Li Dian, Liu Can
Department of Plastic and Reconstruction, The Third Xiangya Hospital of Central South University, Changsha, Hunan Province, China.
Department of Epidemiology, UCLA Fielding School of Public Health, Los Angeles, California, USA.
J Cosmet Dermatol. 2025 Jul;24(7):e70363. doi: 10.1111/jocd.70363.
Along with economic and technological advancements, traditional herbal ingredients have garnered increasing attention in skincare due to their antioxidative properties, low toxicity, multitargeted effects, and broad cultural acceptance. However, there remains a lack of comprehensive knowledge frameworks and systematic research trend analyses in this field. This study examines the scientific landscape and innovation patterns of herbal skincare, aiming to establish a framework for integrating traditional wisdom with modern dermatological science.
A systematic literature search was conducted in the Web of Science Core Collection (SCI-E). CiteSpace, VOSviewer, and ArcGIS were employed to analyze leading contributors, research trends, and thematic evolutions.
The analysis yielded 1593 papers authored by 753 researchers from 507 institutions across 102 countries. China emerged as the top contributor, while Industrial Crops and Products was the most highly cited journal, and Zengin, Gokhan, was the most prolific author. Geographical clustering and cultural convergence characterized the distribution of countries, institutions, and authors. Keyword clustering identified 20 research networks, with recent clusters including #6 "molecular docking," #7 "chromatography-mass spectrometry," and #15 "mixture design." Persistently trending keywords included "Mechanism," "Gut microbiota," "Network pharmacology," and "Association."
Research on herbal skincare has evolved from raw plant usage to advanced refinement techniques, spanning animal, cellular, and molecular studies, including high-throughput screening approaches. Formulations have progressed from complex mixtures to single-compound extractions and bioactive monomers. A comprehensive research system has been established, yet standardization in dosage, application, and manufacturing remains crucial. Future studies should prioritize multicenter clinical trials and evidence-based validation. This study highlights the transition from empirical herbal applications to precision skincare, advocating for global collaboration between traditional medicine and modern regulatory science.
随着经济和技术的进步，传统草药成分因其抗氧化特性、低毒性、多靶点作用以及广泛的文化接受度，在护肤品领域受到越来越多的关注。然而，该领域仍缺乏全面的知识框架和系统的研究趋势分析。本研究考察了草药护肤品的科学现状和创新模式，旨在建立一个将传统智慧与现代皮肤病学科学相结合的框架。
在科学网核心合集（SCI-E）中进行了系统的文献检索。使用CiteSpace、VOSviewer和ArcGIS分析主要贡献者、研究趋势和主题演变。
分析得出1593篇论文，由来自102个国家507个机构的753名研究人员撰写。中国是最大的贡献国，《工业作物与产品》是被引用次数最多的期刊，曾金（Zengin, Gokhan）是最多产的作者。国家、机构和作者的分布呈现出地理聚类和文化趋同的特点。关键词聚类识别出20个研究网络，最近的聚类包括#6“分子对接”、#7“色谱-质谱联用”和#15“混合设计”。持续热门的关键词包括“机制”、“肠道微生物群”、“网络药理学”和“关联”。
草药护肤品的研究已从使用原始植物发展到先进的精制技术，涵盖动物、细胞和分子研究，包括高通量筛选方法。配方已从复杂混合物发展到单化合物提取和生物活性单体。已经建立了一个全面的研究体系，但剂量、应用和生产的标准化仍然至关重要。未来的研究应优先进行多中心临床试验和循证验证。本研究突出了从经验性草药应用到精准护肤的转变，倡导传统医学与现代监管科学之间的全球合作。
