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一名非酒精性患者出现听力丧失和视力丧失的韦尼克脑病

Wernicke Encephalopathy Presenting With Hearing Loss and Vision Loss in a Nonalcoholic Patient.

作者信息

Sim Amy H, Tang Rui, O Neill Thomas J, Piriyawat Paisith

机构信息

Neurology, Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, El Paso, USA.

Neuroradiology, Texas Tech University Health Sciences Center El Paso Paul L. Foster School of Medicine, El Paso, USA.

出版信息

Cureus. 2024 Oct 23;16(10):e72186. doi: 10.7759/cureus.72186. eCollection 2024 Oct.

DOI:10.7759/cureus.72186
PMID:39583405
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11583105/
Abstract

Wernicke encephalopathy is an acute neuropsychiatry syndrome resulting from thiamine deficiency associated with significant morbidity and mortality. We reported a case of a 25-year-old woman with a history of abdomen pain, nausea, vomiting, weight loss, and sore throat who presented with acute neurological symptoms, including binocular diplopia, hearing loss, vision loss, and difficulty ambulating. Examination revealed bilateral vision loss with perception only to light, ophthalmoplegia, hearing loss, gait ataxia, and areflexia. Laboratory work detected multiple vitamin deficiencies. Magnetic resonance imaging (MRI) of the brain showed increased T2 signal in the bilateral medial thalami and periaqueductal areas. Empirical treatment with intravenous thiamine resulted in rapid clinical and radiological resolution.

摘要

韦尼克脑病是一种急性神经精神综合征,由硫胺素缺乏引起,具有较高的发病率和死亡率。我们报告了一例25岁女性病例,该患者有腹痛、恶心、呕吐、体重减轻和喉咙痛病史,出现急性神经症状,包括双眼复视、听力丧失、视力丧失和行走困难。检查发现双侧视力丧失,仅对光有感知,眼肌麻痹,听力丧失,步态共济失调和反射消失。实验室检查发现多种维生素缺乏。脑部磁共振成像(MRI)显示双侧内侧丘脑和导水管周围区域T2信号增强。静脉注射硫胺素的经验性治疗导致临床和影像学迅速恢复。

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