Ohara Yuji, Kido Issei, Nakai Kozo
Department of Dermatology, Kochi Medical School, Kochi University, Kohasu, Oko-cho, Nankoku 783-8505, Kochi, Japan.
Dermatopathology (Basel). 2024 Nov 22;11(4):330-332. doi: 10.3390/dermatopathology11040034.
Akatsuki disease (also known as pomade crust) is characterized by skin lesions resulting from inadequate skin hygiene. It is sometimes influenced by underlying psychological factors. Akatsuki disease sometimes mimics cutaneous horn or skin cancer. However, there are no previous reports of skin cancer accompanied with Akatsuki disease. Herein, we report a 79-year-old woman who was referred to our department with a tumor on her left cheek. Before performing a biopsy, we recommended that her family assist with regular facial cleansing. Two months later, the scales and crusts on her entire face had disappeared and the tumor on the left cheek had reduced. Skin biopsy was performed, and histological examination revealed ulcerative basaloid lobules consisting of cells with a small cytoplasm and large hyperchromatic nuclei. Peripheral palisading and tumor-stroma clefting were observed. A diagnosis of basal cell carcinoma was made.
明月病（也称为润发油痂皮病）的特征是由于皮肤卫生不足导致的皮肤病变。它有时受潜在心理因素影响。明月病有时会模仿皮肤角或皮肤癌。然而，此前尚无明月病伴发皮肤癌的报道。在此，我们报告一名79岁女性，因左侧脸颊出现肿物被转诊至我科。在进行活检之前，我们建议其家人协助进行定期面部清洁。两个月后，她整个面部的鳞屑和痂皮消失，左侧脸颊的肿物缩小。进行了皮肤活检，组织学检查显示为溃疡性基底样小叶，由细胞质小、核大深染的细胞组成。观察到外周栅栏状排列和肿瘤-基质裂隙。诊断为基底细胞癌。
