Diamantis George N, Kim Youngmee, Ofori-Atta Zoe, Devine LaNita, Antoni Michael H, Reyes Vincent, Johnson Jonas, Kiefer Gauri, Jiang Yu, Zandberg Dan P, Nilsen Marci, Tohme Samer, Geller David A, Steel Jennifer L
Department of Surgery, University of Pittsburgh Medical Center.
Department of Psychology, University of Miami.
Health Psychol. 2025 Apr;44(4):391-400. doi: 10.1037/hea0001449. Epub 2024 Nov 25.
To examine the rates as well as the interdependence of depressive symptoms and sleep problems in patients with cancer and their intimate partner family caregivers.
Patients diagnosed with cancer (69.3 years old, 56.9% male) and their intimate family caregivers (63.8 years old, 30.7% male) were enrolled in the study ( = 188 dyads). Both patients and intimate partner family caregivers completed the Center for Epidemiological Studies-Depression and the Pittsburgh Sleep Quality Index. Descriptive statistics and Actor-Partner Interdependence Modeling were used to test the hypotheses.
The rates of depressive symptoms in the clinical range were 39% for patients and 33% in intimate partner family caregivers. A mean of 6.3 ( = 1.9) and 6.5 ( = 1.5) hours of sleep was reported by patients with cancer and intimate partner family caregivers. The mean sleep efficiency (76.6% and 81.3%) and sleep quality (8.25 and 7.2) were poor for both partners. After covarying for age, sex, body mass index, smoking status, pain, and cancer stage, patients' depressive symptoms were associated with their own shorter sleep duration. Patient depressive symptoms were associated with their own and their partners' f poorer sleep efficiency and poorer sleep quality. Caregivers' depressive symptoms were also associated with their own poorer sleep quality.
The mood of both partners affect on sleep, and potentially health, was underscored by the findings. The development of dyadic interventions is warranted to improve both mood and sleep in both the patient and caregivers in the context of cancer. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
研究癌症患者及其亲密伴侣家庭照顾者中抑郁症状和睡眠问题的发生率以及两者之间的相互依存关系。
招募被诊断患有癌症的患者（69.3岁，男性占56.9%）及其亲密家庭照顾者（63.8岁，男性占30.7%）参与研究（共188对）。患者和亲密伴侣家庭照顾者均完成了流行病学研究中心抑郁量表和匹兹堡睡眠质量指数。采用描述性统计和行为者-伴侣相互依存模型来检验假设。
临床范围内患者的抑郁症状发生率为39%，亲密伴侣家庭照顾者为33%。癌症患者及其亲密伴侣家庭照顾者报告的平均睡眠时间分别为6.3（标准差=1.9）小时和6.5（标准差=1.5）小时。双方的平均睡眠效率（分别为76.6%和81.3%）和睡眠质量（分别为8.25和7.2）都很差。在对年龄、性别、体重指数、吸烟状况、疼痛和癌症分期进行协变量调整后，患者的抑郁症状与他们自己较短的睡眠时间有关。患者的抑郁症状与他们自己以及伴侣较差的睡眠效率和较差的睡眠质量有关。照顾者的抑郁症状也与他们自己较差的睡眠质量有关。
研究结果强调了双方的情绪对睡眠以及潜在健康的影响。有必要开展二元干预措施，以改善癌症背景下患者和照顾者的情绪和睡眠。（PsycInfo数据库记录（c）2025美国心理学会，保留所有权利）
