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Absence of immunoreactive interferon-alpha in CSF from patients with multiple sclerosis.

作者信息

Abbott R J, Giles P D, Bolderson I

出版信息

J Neurol Neurosurg Psychiatry. 1986 Jan;49(1):102-3. doi: 10.1136/jnnp.49.1.102.

DOI:10.1136/jnnp.49.1.102
PMID:3958724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1028659/
Abstract
摘要

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1
Absence of immunoreactive interferon-alpha in CSF from patients with multiple sclerosis.多发性硬化症患者脑脊液中无免疫反应性α干扰素。
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2
Hypothesis: multiple sclerosis is a type I interferon deficiency syndrome.假说：多发性硬化症是一种I型干扰素缺乏综合征。
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Serial immunological studies in multiple sclerosis patients treated systemically with human alpha interferon.对接受人α干扰素全身治疗的多发性硬化症患者进行的系列免疫学研究。
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Measurement of binding anti-IFNbeta antibodies in IFNbeta-treated MS patients: lessons for the clinician and basic scientist.干扰素β治疗的多发性硬化症患者中抗干扰素β结合抗体的检测：给临床医生和基础科学家的启示
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Treatment of multiple sclerosis with various interferons: the cons.使用多种干扰素治疗多发性硬化症：反对观点
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Endogenous interferon-β-inducible gene expression and interferon-β-treatment are associated with reduced T cell responses to myelin basic protein in multiple sclerosis.内源性干扰素-β诱导基因表达和干扰素-β治疗与多发性硬化症中T细胞对髓鞘碱性蛋白的反应降低有关。
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Microheterogeneity of CSF alpha 2-macroglobulin in multiple sclerosis and other neurological diseases. A study performed by direct immunofixation after isoelectric focusing.
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引用本文的文献

1
Immunoreactive IFN-gamma in CSF in neurological disorders.神经系统疾病患者脑脊液中免疫反应性γ-干扰素
J Neurol Neurosurg Psychiatry. 1987 Jul;50(7):882-5. doi: 10.1136/jnnp.50.7.882.

本文引用的文献

1
Defective production of interferon-alpha associated with HLA-DW2 antigen in stable multiple sclerosis.稳定型多发性硬化症中与HLA - DW2抗原相关的α干扰素产生缺陷
J Neurol Sci. 1982 Aug;55(2):197-206. doi: 10.1016/0022-510x(82)90101-0.
2
New diagnostic criteria for multiple sclerosis: guidelines for research protocols.多发性硬化症的新诊断标准：研究方案指南。
Ann Neurol. 1983 Mar;13(3):227-31. doi: 10.1002/ana.410130302.
3
Intrathecal interferon in multiple sclerosis.多发性硬化症中的鞘内注射干扰素
Arch Neurol. 1982 Oct;39(10):609-15. doi: 10.1001/archneur.1982.00510220007002.
4
Serum interferon levels and natural killer cell activity in patients with asbestosis.石棉沉着病患者的血清干扰素水平及自然杀伤细胞活性
Thorax. 1984 Jan;39(1):65-6. doi: 10.1136/thx.39.1.65.
5
CSF and serum interferon in multiple sclerosis: longitudinal study.多发性硬化症中的脑脊液和血清干扰素：纵向研究
Neurology. 1983 Dec;33(12):1604-6. doi: 10.1212/wnl.33.12.1604.
6
Interferon production by lymphocytes from multiple sclerosis and non-MS patients.来自多发性硬化症患者和非多发性硬化症患者的淋巴细胞产生干扰素的情况。
Neurology. 1983 May;33(5):640-3. doi: 10.1212/wnl.33.5.640.
7
Cytotoxic activity and interferon production by lymphocytes from patients with multiple sclerosis.多发性硬化症患者淋巴细胞的细胞毒性活性和干扰素产生
J Immunol. 1981 Apr;126(4):1274-8.
8
Rapid detection of immunoreactive interferon-alpha in AIDS.艾滋病中免疫反应性α干扰素的快速检测
Lancet. 1984 Mar 10;1(8376):564. doi: 10.1016/s0140-6736(84)90959-0.
9
Virus-inhibiting activity in the cerebro-spinal fluid from patients with acute and chronic neurological diseases.急性和慢性神经疾病患者脑脊液中的病毒抑制活性。
Acta Pathol Microbiol Scand B Microbiol Immunol. 1971;79(4):606-8. doi: 10.1111/j.1699-0463.1971.tb03819.x.
10
Interferon in the serum and cerebrospinal fluid in patients with multiple sclerosis and other neurological disorders.多发性硬化症及其他神经系统疾病患者血清和脑脊液中的干扰素。
Acta Neurol Scand. 1976 Feb;53(2):152-60. doi: 10.1111/j.1600-0404.1976.tb04333.x.