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[血压升高与高血压:2024年欧洲心脏病学会降低风险指南的重点]

[Elevated blood pressure and hypertension : Focus of the 2024 ESC guidelines on risk reduction].

作者信息

Schmieder Raphael S, Schunkert Heribert

机构信息

Klinik für Herz- und Kreislauferkrankungen, Deutsches Herzzentrum München (DHM), Universitätsklinikum der Technischen Universität München, Lazarettstr. 36, 80636, München, Deutschland.

Deutsches Zentrum für Herz- und Kreislauf-Forschung (DZHK) e. V. (German Center for Cardiovascular Research), Partner Site Munich Heart Alliance, München, Deutschland.

出版信息

Herz. 2025 Feb;50(1):17-24. doi: 10.1007/s00059-024-05285-8. Epub 2024 Nov 26.

Abstract

The 2024 guidelines of the European Society of Cardiology (ESC) for the management of elevated blood pressure and hypertension introduce the new category "elevated blood pressure" (120-139/70-89 mm Hg). All patients with elevated blood pressure are advised to implement lifestyle modifications. The aim is to reduce the cardiovascular risk at an early stage. In addition, a structured assessment should be carried out based on the comorbidities, such as coronary artery disease, heart failure and stroke as well as on risk factors, which can result from an antihypertensive treatment in cases of moderate to high risk and a blood pressure of 130/80 mm Hg or more despite 3 months of lifestyle modifications. For patients with hypertension (≥ 140/90 mm Hg), the guidelines now recommend initiating lifestyle modifications and antihypertensive medication concurrently. The new target systolic blood pressure is 120-129 mm Hg, with establishment of individualized treatment goals in cases of frailty or age ≥85 years. Compared to the guidelines of the European Society of Hypertension (ESH) and the German national guidelines (NVL), the ESC extends the treatment recommendations to patients with elevated blood pressure even below the threshold of 140/90 mm Hg. For resistant hypertension spironolactone is recommended, with renal denervation being an alternative option to increasing the antihypertensive medication.

摘要

欧洲心脏病学会(ESC)2024年高血压管理指南引入了新类别“血压升高”(120 - 139/70 - 89 mmHg)。建议所有血压升高的患者进行生活方式调整。目的是在早期降低心血管风险。此外,应根据合并症(如冠状动脉疾病、心力衰竭和中风)以及风险因素进行结构化评估,对于中高危患者,尽管进行了3个月的生活方式调整,但血压仍为130/80 mmHg或更高时,这些风险因素可能由降压治疗引起。对于高血压患者(≥140/90 mmHg),指南现在建议同时启动生活方式调整和降压药物治疗。新的收缩压目标是120 - 129 mmHg,对于身体虚弱或年龄≥85岁的患者,应制定个体化治疗目标。与欧洲高血压学会(ESH)指南和德国国家指南(NVL)相比,ESC将治疗建议扩展到血压升高甚至低于140/90 mmHg阈值的患者。对于难治性高血压,推荐使用螺内酯,肾去神经支配是增加降压药物之外的另一种选择。

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