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牛、猪和人的心包壁层作为心脏瓣膜生物假体材料的比较电子显微镜研究。

Comparative electron microscopic study of bovine, porcine and human parietal pericardium, as materials for cardiac valve bioprostheses.

作者信息

Fentie I H, Allen D J, Schenck M H, Didio L J

出版信息

J Submicrosc Cytol. 1986 Jan;18(1):53-65.

PMID:3959161
Abstract

Light, scanning and transmission electron microscopy were used in the comparison of bovine, porcine and human parietal pericardium. Bovine pericardium is widely used for heart valve bioprosthesis, is thicker than the other two, and has more coarse connective tissue fiber components, whereas porcine pericardium possesses relatively larger quantities of fat cells in regular layers. Human tissue is thinner than either the bovine or porcine parietal pericardium and its mesothelium seems less delicate. The human tissue, being thinner, may provide a source of materials for valves with significant hemodynamic characteristics. Such material might be used to produce small diameter valves directed towards younger patients. Though the literature does not mention its usage, porcine pericardium is of intermediate thickness and it too may serve in the future as a construction material for valve bioprostheses.

摘要

运用光镜、扫描电镜和透射电镜对牛、猪和人的壁层心包进行了比较。牛心包广泛用于心脏瓣膜生物假体,比其他两者厚,且有更多粗大的结缔组织纤维成分,而猪心包有规则层状排列的相对较多的脂肪细胞。人体组织比牛或猪的壁层心包薄,其间皮似乎不那么细腻。人体组织较薄,可能为具有显著血流动力学特性的瓣膜提供材料来源。这种材料可用于制造针对年轻患者的小直径瓣膜。虽然文献未提及猪心包的用途,但它厚度适中,未来也可能用作瓣膜生物假体的构建材料。

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