State University of Santa Catarina (UDESC), Graduate Program in Human Movement Sciences, Brazil.
State University of Santa Catarina (UDESC), Graduate Program in Human Movement Sciences, Brazil.
J Bodyw Mov Ther. 2024 Oct;40:1782-1790. doi: 10.1016/j.jbmt.2024.10.010. Epub 2024 Oct 5.
Over the years, human activity and performance show a normal decline in cognitive and sensorimotor tasks.
To identify physical activity strategies for mild cognitive impairment (MCI) and describe their main predictors during aging.
This systematic review identified the outcomes of physical activity strategies used in MCI and described their main predictors during aging. It was conducted using PubMed/MEDLINE, Scopus, LILACS, SPORTDiscus and Embase databases. The risk of bias analysis was adapted from the Cochrane handbook manual scale for experimental studies.
Twenty-one studies were qualitatively analyzed, the sample total included 2023 older adults, which revealed the main predictors of MCI to be changes in glycated hemoglobin, brain-derived neurotrophic factor, and vascular endothelial growth factor-induced neovascularization. As a strategy for learning and presynaptic plasticity in the ageing population, the intervention should be conducted in a regular and moderate way, prioritizing memory and executive function with light exercises.
Health professionals be aware of the predictors highlighted in this study, as well as the strategies that can be used in clinical practice to enhance the functionality of these individuals, seeking greater social bonding, autonomy and a sense of competence. Future research should be conducted with strong methodological rigor to investigate more predictors and effective strategies to improve the quality of life of this population, since more precise mechanisms on how to introduce changes in the cortical areas of memory, based on strategies with specific characteristics of MCI, are still something to be explored.
多年来，人类的活动和表现显示出认知和感觉运动任务的正常下降。
确定轻度认知障碍（MCI）的身体活动策略，并描述其在衰老过程中的主要预测因素。
本系统评价确定了用于 MCI 的身体活动策略的结果，并描述了其在衰老过程中的主要预测因素。使用 PubMed/MEDLINE、Scopus、LILACS、SPORTDiscus 和 Embase 数据库进行检索。对偏倚风险的分析是根据 Cochrane 手册实验研究的规模进行调整的。
21 项研究进行了定性分析，样本总人数包括 2023 名老年人，结果表明 MCI 的主要预测因素是糖化血红蛋白、脑源性神经营养因子和血管内皮生长因子诱导的血管新生的变化。作为老龄化人群学习和突触前可塑性的策略，干预应该以有规律和适度的方式进行，优先考虑记忆和执行功能，进行轻度运动。
健康专业人员应该注意到本研究中强调的预测因素，以及可以在临床实践中使用的策略，以增强这些个体的功能，寻求更大的社会联系、自主性和成就感。未来的研究应具有严格的方法学严谨性，以调查更多的预测因素和有效的策略，提高这一人群的生活质量，因为如何根据 MCI 的特定特征引入记忆皮质区域的变化的更精确机制仍有待探索。
