Hepatibiliopancreatic and Transplant Department, General and Digestive Surgery, Hospital Clinic, University of Barcelona, C. Villarroel, 170, 08036 Barcelona, Spain.
Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), 08036 Barcelona, Spain.
Medicina (Kaunas). 2024 Nov 1;60(11):1798. doi: 10.3390/medicina60111798.
: Biliary fistulas (BFs) occur in approximately 3-8% of patients undergoing pancreaticoduodenectomy (PD), and the bile duct diameter ≤ 5 mm is the most important risk factor. The aim of this study was to evaluate the efficacy of biodegradable biliary stents (BSs) in reducing complications in patients undergoing robotic pancreaticoduodenectomy (RPD) with a bile duct diameter of ≤5 mm. : A retrospective single-centre observational study was conducted. Patients undergoing RPD after the completion of the robotic biliary anastomosis learning curve were included in this study. Only patients with a bile duct diameter ≤ 5 mm were included in the analysis. A prospectively held database was used. The intraoperative time for biliary anastomosis was extracted from surgical videos. : Of 30 patients, 20 received no biliary stent (nBS) and 10 received a biodegradable stent (BS). The decision to use a stent was based on product availability. The median operative time for biliary anastomosis was significantly shorter in the BS group compared to the nBS group, at 15 min versus 24 min ( < 0.001). Three patients in the nBS group developed a BF, whereas none were observed in the BS group. No stent migration was observed in any of the patients. : The use of biodegradable biliary stents in high-risk biliary anastomosis in RPD appears to effectively reduce the incidence of BFs and may serve as a viable strategy to mitigate early biliary complications. The use of biodegradable stents facilitates a faster and easier biliary anastomosis. These findings suggest a potential benefit of using biodegradable stents in complex biliary reconstruction. However, larger studies are needed to confirm these results.
胆管瘘(BFs)在接受胰十二指肠切除术(PD)的患者中约占 3-8%,而胆管直径≤5mm 是最重要的危险因素。本研究旨在评估生物可降解胆管支架(BSs)在减少胆管直径≤5mm 的机器人胰十二指肠切除术(RPD)患者并发症方面的疗效。
这是一项回顾性单中心观察性研究。本研究纳入了完成机器人胆道吻合学习曲线后的 RPD 患者。仅对胆管直径≤5mm 的患者进行分析。使用前瞻性保存的数据库。从手术视频中提取胆管吻合的手术时间。
在 30 名患者中,20 名未接受胆管支架(nBS),10 名接受生物可降解支架(BS)。支架的使用决定基于产品可用性。BS 组的胆管吻合手术时间明显短于 nBS 组,分别为 15 分钟和 24 分钟(<0.001)。nBS 组有 3 名患者发生 BF,而 BS 组则没有。没有患者观察到支架迁移。
在 RPD 中,在高危胆道吻合中使用生物可降解胆管支架似乎可以有效降低 BF 的发生率,并可能成为减轻早期胆道并发症的可行策略。生物可降解支架的使用有利于更快、更容易的胆道吻合。这些发现表明,在复杂的胆道重建中使用生物可降解支架可能具有潜在的益处。然而,需要更大的研究来证实这些结果。