Licea-Herrera Jessica I, Guerrero Abraham, Mireles-Martínez Maribel, Rodríguez-González Yuridia, Aguilera-Arreola Guadalupe, Contreras-Rodríguez Araceli, Fernandez-Davila Susana, Requena-Castro Rocío, Rivera Gildardo, Bocanegra-García Virgilio, Martínez-Vázquez Ana Verónica
Centro de Biotecnología Genómica, Instituto Politécnico Nacional, Reynosa 88710, Tamaulipas, Mexico.
Consejo Nacional de Ciencia y Tecnología (CONAHCyT), Centro de Investigación en Alimentación y Desarrollo (CIAD), Mazatlán 82100, Sinaloa, Mexico.
Microorganisms. 2024 Oct 30;12(11):2181. doi: 10.3390/microorganisms12112181.
is an opportunistic pathogen with a high capacity to adapt to different factors. The aim of this study is to analyze the pathogenicity in strains and their resistance to heavy metals and antibiotics, in agricultural soil of the state of Tamaulipas, Mexico. Susceptibility to 16 antibiotics was tested using the Kirby-Bauer method (CLSI). Eight virulence factors (FV) and six genes associated with heavy metal resistance were detected by PCR. As a result, was detected in 55% of the samples. The eight virulence factors were identified in ≥80% of the strains. The strains showed some level of resistance to only three antibiotics: 32.8% to ticarcillin, 40.8% to ticarcillin/clavulanic acid and 2.4% to aztreonam. The most frequent heavy metal resistance genes were C (92.8%) and A (90.4%). However, B and B genes were also identified in a percentage greater than 80%, and the least frequent genes were A in 14.4% and A in 7.2%. Although strains showed a high percentage of factor virulence (potential ability to cause infections), their high levels of susceptibility to antibiotics lead to the assumption that infections are easily curable.
是一种具有高度适应不同因素能力的机会致病菌。本研究的目的是分析墨西哥塔毛利帕斯州农业土壤中菌株的致病性及其对重金属和抗生素的抗性。使用 Kirby-Bauer 方法(CLSI)检测对 16 种抗生素的敏感性。通过 PCR 检测了 8 种毒力因子(FV)和 6 种与重金属抗性相关的基因。结果,在 55%的样本中检测到了 。在≥80%的菌株中鉴定出了这 8 种毒力因子。这些菌株仅对三种抗生素表现出一定程度的抗性:对替卡西林的抗性为 32.8%,对替卡西林/克拉维酸的抗性为 40.8%,对氨曲南的抗性为 2.4%。最常见的重金属抗性基因是 C(92.8%)和 A(90.4%)。然而,B 和 B 基因的鉴定比例也大于 80%,最不常见的基因是 A,占 14.4%,A 占 7.2%。尽管 菌株表现出较高比例的毒力因子(引起感染的潜在能力),但其对抗生素的高敏感性导致人们认为感染很容易治愈。