Efficacy of dermapen combined with topical insulin versus dermapen combined with topical hyaluronic acid in treatment of stretch marks: comparative study.

Striae distensae (SD) are visible linear scars developing in areas of dermal damage. Insulin is a peptide hormone that can potentially help restore the integrity of damaged skin and promote the reformation of granulation tissue. Hyaluronic Acid is commonly used in aesthetic medicine. To evaluate the clinical response and efficacy of microneedling and topical insulin against microneedling and topical hyaluronic acid in treating stretch marks. The study was conducted on 30 patients suffering from striae distensae in the abdomen. The patients were treated by microneedling followed by hyaluronic acid on the right side. The second group was treated by microneedling followed by topical insulin on the left side of the abdomen. At the end of the study the improvement with hyaluronic acid was 23.3% of patients with excellent improvement and 30.0% of patients with marked improvement. The improvement with topical insulin was 30.0% of patients with excellent improvement and 20.0% of patients with marked improvement. Microneedling followed by hyaluronic acid or topical insulin can be an effective and safe therapeutic option for the treatment of Stretch marks with no significant side effects.