Washington Institute of Dermatologic Laser Surgery, Washington, DC.
MKL Dermatology, Vancouver, British Columbia, Canada.
Dermatol Surg. 2020 Apr;46(4):459-464. doi: 10.1097/DSS.0000000000002081.
Striae distensae have notoriously been difficult to treat due to their extensive involvement of nonfacial skin. Microneedling with its lack of thermal injury during microneedling treatment renders it a viable treatment option in darker skin tones and nonfacial regions due to the reduced risk of postinflammatory hyperpigmentation.
To describe the clinical results and side effects of microneedling in a series of 25 individuals with striae distensae.
Twenty-five consecutive adults (SPT I-V) with striae distensae involving the trunk and extremities were treated using a microneedling device. No additional treatments (topical or intralesional) were applied. Two assessors blinded to treatment protocol rated clinical improvement of striae on a 5-point scale. Side effects were monitored and tabulated.
Patients received 1 to 3 consecutive monthly treatments. All striae improved at least 50% after an average of 1.8 treatments, and 28% of patients demonstrated more than 75% clinical improvement. Striae in thicker skin regions (e.g., buttocks/thighs) showed comparable clinical improvement than those in thinner skin areas (e.g., breasts) and did not require additional treatment sessions. Side effects were limited to transient erythema in all skin phototypes. No infections or dyspigmentation were observed.
The clinical results obtained in this study support the safe and effective treatment of striae distensae with microneedling in light and dark skin tones in various body locations. Standardization of treatment protocols are anticipated with further (ongoing) studies.
由于广泛涉及非面部皮肤，妊娠纹的治疗一直很困难。微针治疗在微针治疗过程中不会造成热损伤，因此在深色皮肤和非面部区域由于减少了炎症后色素沉着过度的风险，成为一种可行的治疗选择。
描述微针治疗一系列 25 例妊娠纹患者的临床效果和副作用。
25 例连续的成年人（SPT I-V），躯干和四肢有妊娠纹，使用微针设备进行治疗。未应用其他治疗（局部或病灶内）。两名评估者根据治疗方案对妊娠纹的临床改善程度进行了 5 分制评分。监测并记录副作用。
患者接受了 1 到 3 次连续的每月治疗。所有妊娠纹在平均 1.8 次治疗后至少改善了 50%，28%的患者表现出超过 75%的临床改善。较厚皮肤区域（如臀部/大腿）的妊娠纹与较薄皮肤区域（如乳房）的妊娠纹具有相似的临床改善效果，且无需额外的治疗次数。所有皮肤类型的副作用均局限于短暂的红斑。未观察到感染或色素沉着不均。
本研究的临床结果支持在各种身体部位的浅色和深色皮肤中使用微针治疗妊娠纹的安全性和有效性。随着进一步（正在进行）的研究，预计会制定出治疗方案的标准化。
