Zeng Qingjia, Zhang Chongyang, Liu Xinyao, Yang Shengmin, Ma Muyuan, Tang Jia, Yin Tianlu, Zhao Shanshan, Tu Wenjun, Hu Hongpu
Institute of Medical Information/Medical Library, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, 100020, China.
Key Laboratory of Endocrinology of National Health Commission, Department of Endocrinology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College, Beijing, 100730, China.
Front Med. 2025 Feb;19(1):64-78. doi: 10.1007/s11684-024-1088-0. Epub 2024 Nov 27.
Stroke is a critical health issue in China, and carotid artery stenosis and plaque play key roles in its prevalence. Despite the acknowledged significance of this condition, detailed information regarding the prevalence of carotid artery stenosis and plaque across the Chinese population has been scarce. This study analyzed data from the China Stroke High-risk Population Screening and Intervention Program for 2020-2021, focusing on 194 878 Chinese adults aged 40 years and above. It assessed the prevalence of carotid artery stenosis and plaque and identified their associated risk factors. Results revealed a standardized prevalence of 0.40% for carotid artery stenosis and 36.27% for carotid plaque. Notably, the highest rates of stenosis were observed in north and south China at 0.61%, while southwestern China exhibited the highest plaque prevalence at 43.17%. Key risk factors included older age, male gender, hypertension, diabetes, stroke, smoking, and atrial fibrillation. This study highlights significant geographical and demographic disparities in the prevalence of these conditions, underlining the urgent need for targeted interventions and policy reforms. These measures are essential for reducing the incidence of stroke and improving patient outcomes, addressing this significant health challenge in China.
中风在中国是一个严重的健康问题，颈动脉狭窄和斑块在其发病中起着关键作用。尽管人们认识到这种情况的重要性，但关于中国人群中颈动脉狭窄和斑块患病率的详细信息却很少。本研究分析了2020 - 2021年中国中风高危人群筛查与干预项目的数据，重点关注了194878名40岁及以上的中国成年人。该研究评估了颈动脉狭窄和斑块的患病率，并确定了其相关风险因素。结果显示，颈动脉狭窄的标准化患病率为0.40%，颈动脉斑块的患病率为36.27%。值得注意的是，中国北方和南方的狭窄率最高，为0.61%，而中国西南部的斑块患病率最高，为43.17%。主要风险因素包括年龄较大、男性、高血压、糖尿病、中风、吸烟和心房颤动。这项研究突出了这些疾病患病率在地理和人口统计学上的显著差异，强调了针对性干预和政策改革的迫切需求。这些措施对于降低中风发病率和改善患者预后至关重要，有助于应对中国这一重大的健康挑战。
