Bonnet M H
Neurobiol Aging. 1986 Mar-Apr;7(2):89-96. doi: 10.1016/0197-4580(86)90145-4.
Fifty-eight geriatric normal and chronic insomniac sleepers were screened with sleep recordings to define groups of 12 Normal (Sleep Efficiency greater than 85%) and Insomniac (Sleep Efficiency less than 80%) sleepers. All subjects then had 4 baseline sleep nights, 64 hours of total sleep loss, and 4 recovery nights. Insomniacs, had lower sleep efficiencies and less REM than Normals during baseline. Sleep efficiency was high (97%) in both groups on the first recovery night but decreased toward baseline values in both groups between the second (Normal) and fourth (Insomniac) recovery night. The groups had relatively little slow wave sleep, but had a significant increase on the first recovery night. Five Normals and one Insomniac had REM latency of less than 15 min on their first recovery night. This REM latency was found to be significantly correlated with the amount of slow wave sleep on baseline. Decreased REM latency in initial recovery sleep was interpreted as evidence of decreased pressure for slow wave sleep in aging.
对58名老年正常睡眠者和慢性失眠睡眠者进行睡眠记录筛查，以确定12名正常睡眠者（睡眠效率大于85%）和失眠睡眠者（睡眠效率小于80%）的组别。所有受试者随后经历4个基线睡眠夜晚、64小时的总睡眠剥夺以及4个恢复夜晚。在基线期，失眠者的睡眠效率低于正常睡眠者，且快速眼动睡眠较少。在第一个恢复夜晚，两组的睡眠效率都很高（97%），但在第二个（正常睡眠者）和第四个（失眠者）恢复夜晚之间，两组的睡眠效率均朝着基线值下降。两组的慢波睡眠相对较少，但在第一个恢复夜晚有显著增加。5名正常睡眠者和1名失眠者在第一个恢复夜晚的快速眼动睡眠潜伏期小于15分钟。发现这种快速眼动睡眠潜伏期与基线期的慢波睡眠量显著相关。初始恢复睡眠中快速眼动睡眠潜伏期的缩短被解释为衰老过程中慢波睡眠压力降低的证据。
