Universidade de São Paulo - USP, School of Dentistry, Department of Stomatology, São Paulo, SP, Brazil.
Universidad Peruana Cayetano Heredia, Academic Department of Clinical Stomatology, Lima, Perú.
Braz Oral Res. 2024 Oct;38(suppl 1):e118. doi: 10.1590/1807-3107bor-2024.vol38.0118.
There is scarcity of information on the determinants of periodontitis in Latin America and Caribbean countries. We conducted a comprehensive review of studies examining the association of smoking and diabetes with periodontitis outcomes in this region. We searched for population-based, cross-sectional and prospective cohort studies from Latin America and the Caribbean region that reported on the association between smoking or diabetes and periodontitis. Databases were searched up to October 2023 by two reviewers. Subsequently, two authors independently conducted a rigorous data extraction process, focusing on study characteristics, the definition of exposures, and periodontitis outcomes, including measures of association and main findings. The results revealed a significant association between smoking and periodontitis, with a stronger effect observed in heavy smokers. Conversely, while some studies observed a higher prevalence of periodontitis among diabetic individuals, the association between diabetes and periodontitis was not significant after adjusting for confounding factors. These findings underscore a significant research gap in population-based studies on the effect of smoking and diabetes on periodontitis within Latin American and Caribbean countries, particularly when it comes to cohort studies. Addressing these gaps is crucial for a deeper understanding of these associations, which could lead to more effective prevention and treatment strategies in the region.
关于拉丁美洲和加勒比国家牙周炎的决定因素的信息很少。我们对检查吸烟和糖尿病与该地区牙周炎结果之间关联的研究进行了全面审查。我们在拉丁美洲和加勒比地区搜索了基于人群的、横断面和前瞻性队列研究,这些研究报告了吸烟或糖尿病与牙周炎之间的关系。两名审查员对数据库进行了截至 2023 年 10 月的搜索。随后,两名作者独立进行了严格的数据提取过程,重点关注研究特征、暴露定义和牙周炎结果,包括关联措施和主要发现。结果表明,吸烟与牙周炎之间存在显著关联,重度吸烟者的影响更强。相反,虽然一些研究观察到糖尿病患者中牙周炎的患病率较高,但在调整了混杂因素后,糖尿病与牙周炎之间的关联并不显著。这些发现突显了在拉丁美洲和加勒比国家中,基于人群的关于吸烟和糖尿病对牙周炎影响的研究存在重大差距,特别是在队列研究方面。解决这些差距对于更深入了解这些关联至关重要,这可能会导致该地区更有效的预防和治疗策略。