Center for Health Technology Assessment, Semmelweis University, Üllői út 25, Budapest, 1091, Hungary.
Syreon Research Institute, Mexikói út 65, Budapest, 1142, Hungary.
Qual Life Res. 2024 Sep;33(9):2417-2428. doi: 10.1007/s11136-024-03699-9. Epub 2024 Jun 5.
Although population norms of the EQ-5D-3L instrument had been available in Hungary since 2000, their evaluation was based on a United Kingdom (UK) value set. Our objective was to estimate the population norms for EQ-5D-3L by using the new Hungarian value set available since 2020, to extend the scope to adolescents, and to compare with norms from 2000.
A cross sectional EQ-5D-3L survey representative of the Hungarian population was conducted in 2022. The EQ-5D-3L dimensional responses were analyzed by age and sex and compared with the survey from 2000, by estimating population frequencies with their 95% confidence intervals; index values were evaluated by both value sets.
Altogether, 11,910 respondents, aged 12 or more (578 between 12 and 17), completed the EQ-5D-3L. There was a notable improvement in reporting problems for both sexes (age 35-64) regarding the pain/discomfort and anxiety/depression compared to 2000. Below the age 44, both sexes had an EQ-5D-3L index plateau of 0.98, while above the age 55, men tended to have numerically higher index values compared to women, with the difference increasing with older age. Improvement in dimensional responses were also translated to numerically higher index values for both sexes between ages 18 and 74 compared to 2000. Multivariate regression analysis showed that higher educational attainment, lower age, larger household size, and active occupational status were associated with higher index values.
Over the past 22 years, there was a large improvement in HRQoL of the middle-aged to elderly men and women in Hungary.
尽管自 2000 年以来，匈牙利已经有了 EQ-5D-3L 工具的人口标准，但它们的评估是基于英国（UK）价值体系的。我们的目的是使用自 2020 年以来新的匈牙利价值体系来估计 EQ-5D-3L 的人口标准，将范围扩大到青少年，并与 2000 年的标准进行比较。
2022 年进行了一项具有代表性的 EQ-5D-3L 横断面调查，以反映匈牙利人口。通过年龄和性别分析 EQ-5D-3L 的维度反应，并通过估计人口频率及其 95%置信区间与 2000 年的调查进行比较；通过两种价值体系评估指数值。
共有 11910 名年龄在 12 岁或以上（12-17 岁之间有 578 人）的受访者完成了 EQ-5D-3L 调查。与 2000 年相比，两性（35-64 岁）在疼痛/不适和焦虑/抑郁方面报告问题的情况明显改善。在 44 岁以下，两性的 EQ-5D-3L 指数都处于 0.98 的平台期，而在 55 岁以上，男性的指数值通常高于女性，随着年龄的增长，这种差异也在增加。在 18 岁至 74 岁之间，与 2000 年相比，两性的维度反应的改善也转化为指数值的数值增加。多变量回归分析表明，较高的教育程度、较低的年龄、较大的家庭规模和活跃的职业状态与较高的指数值相关。
在过去的 22 年里，匈牙利中年至老年男性和女性的 HRQoL 有了很大的提高。
