Fatollahzade Mahdie, Bastan Mohammad-Mahdi, Shaabanian Moez, Golestani Ali, Tabatabaei-Malazy Ozra, Mohajeri-Tehrani MohammadReza, Amini MohammadReza, Khosravi Sepehr, Pajavand Hamid, Larijani Bagher
Non-Communicable Diseases Research Center, Endocrinology and Metabolism Population Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Endocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
J Diabetes Metab Disord. 2024 Sep 9;23(2):2207-2224. doi: 10.1007/s40200-024-01489-1. eCollection 2024 Dec.
The significant health differences between sexes in Iran in terms of burden of non-communicable diseases (NCDs) point to the urgency of developing policies. We aim to explore sex disparities in NCDs.
We used Global Burden of Disease 2019 study to compare estimates of incidence, prevalence, disability-adjusted life years (DALYs), years lived with disabilities (YLDs), years of life lost (YLLs), and deaths among sexes for NCDs, and their main subgroups; neoplasms, cardiovascular diseases (CVDs), chronic respiratory diseases (CRDs), diabetes mellitus (DM) during 1990-2019.
In 2019, there were 62,476,274 (59517167.5, 65759931) incident NCDs in men and 78758640.6 (75222093.7, 82272935.8) in women. There were 7734064.3 (6744951.2, 8846192) DALYs in men and 7760484.2 (6496609, 9218299.9) in women. Fatal estimates (deaths and YLLs) of NCDs were higher for men, while non-fatal estimates (prevalence, YLDs) were higher for women. Men were superior in all burden indices of NCDs subgroups, except for all indices of DM and YLDs in CVDs. Compared to 1990-2010, the period 2010-2019 confirmed a marked stagnation in decline rates of burden indices, as well as an increase in incidence and prevalence which was more pronounced among men. Despite shrinking sex gaps in NCDs subgroups since 1990, sex gap in DM is widening in 2019.
There is a notable sex disparity in NCDs prevalence in Iran, which has become increasingly evident in DM burden. It will be imperative to continue monitoring sexual differences in NCDs burden to determine if disease rates between sexes continue to diverge in the future.
The online version contains supplementary material available at 10.1007/s40200-024-01489-1.
伊朗非传染性疾病（NCDs）负担方面存在显著的性别健康差异，这凸显了制定政策的紧迫性。我们旨在探讨非传染性疾病中的性别差异。
我们使用《2019年全球疾病负担研究》来比较1990 - 2019年期间非传染性疾病及其主要亚组（肿瘤、心血管疾病（CVDs）、慢性呼吸道疾病（CRDs）、糖尿病（DM））在性别间的发病率、患病率、伤残调整生命年（DALYs）、带病生存年数（YLDs）、寿命损失年数（YLLs）和死亡人数的估计值。
2019年，男性新发非传染性疾病62,476,274例（59,517,167.5，65,759,931），女性为78,758,640.6例（75,222,093.7，82,272,935.8）。男性的伤残调整生命年为7,734,064.3例（6,744,951.2，8,846,192），女性为7,760,484.2例（6,496,609，9,218,299.9）。非传染性疾病的致命估计值（死亡人数和寿命损失年数）男性更高，而非致命估计值（患病率、带病生存年数）女性更高。除糖尿病的所有指标以及心血管疾病中的带病生存年数指标外，男性在非传染性疾病亚组的所有负担指标上均占优。与1990 - 2010年相比，2010 - 2019年期间负担指标下降率明显停滞，发病率和患病率上升，且在男性中更为明显。尽管自1990年以来非传染性疾病亚组中的性别差距在缩小，但2019年糖尿病的性别差距正在扩大。
伊朗非传染性疾病患病率存在显著的性别差异，在糖尿病负担方面愈发明显。必须持续监测非传染性疾病负担中的性别差异，以确定未来两性之间的疾病率是否会继续分化。
在线版本包含可在10.1007/s40200 - 024 - 01489 - 1获取的补充材料。
