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调查中国江苏地区家长对呼吸道合胞病毒(RSV)的认知及对RSV疫苗的态度:一项横断面研究的见解

Investigating parental perceptions of respiratory syncytial virus (RSV) and attitudes to RSV vaccine in Jiangsu, China: Insights from a cross-section study.

作者信息

Wang Qiang, Yang Liuqing, Li Lan, Xiu Shixin, Yang Min, Wang Xuwen, Shen Yuan, Wang Weibing, Lin Leesa

机构信息

Department of Epidemiology, School of Public Health, Fudan University, Shanghai 200032, China.

Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210009, China.

出版信息

Vaccine. 2025 Jan 12;44:126570. doi: 10.1016/j.vaccine.2024.126570. Epub 2024 Nov 29.

DOI:10.1016/j.vaccine.2024.126570
PMID:39612804
Abstract

INTRODUCTION

Our study aimed to assess parents' perceptions of respiratory syncytial virus (RSV) and their attitudes towards the RSV vaccine in China.

METHOD

The cross-section study was performed between August 21 and November 15, 2023, in Jiangsu province, eastern China. We collected socio-demographics, awareness, knowledge, perceptions of susceptibility and severity of RSV, and attitudes towards RSV vaccine using online survey questionnaire from parents of child aged ≤14 years old. The chi-square test and logistic regression model to explore the associated factors.

RESULTS

A total of 2135 participants were included. About 26.0 % indicated that they had never heard of RSV (556/2135) and were unaware that infants and young children are at a high risk of contracting RSV (557/2135). The proportion of parents with a child under 1 year of age who were unaware of RSV was notably higher than that of parents with children in other age groups. 42.9 % of parents (916/2135) showed low level of perceived susceptibility of contacting RSV infection for their child. 70.6 % of parents (1508/2135) expressed their willingness to vaccinate their child against RSV. The most common reason for refusing the RSV vaccine was "Concern about vaccine's safety or side effects." 60.8 % of participants (1299/2135) considered a price of the RSV vaccine below 200 CNY (28 USD) as acceptable.

CONCLUSION

The parents, particularly those with younger children, exhibited limited awareness and knowledge regarding RSV infection. Our study also showed the potential role of vaccine price as a barrier to the future use of RSV vaccine in China.

摘要

引言

我们的研究旨在评估中国家长对呼吸道合胞病毒(RSV)的认知以及他们对RSV疫苗的态度。

方法

这项横断面研究于2023年8月21日至11月15日在中国东部的江苏省进行。我们通过在线调查问卷收集了14岁及以下儿童家长的社会人口统计学信息、认知情况、知识水平、对RSV易感性和严重性的看法以及对RSV疫苗的态度。采用卡方检验和逻辑回归模型来探索相关因素。

结果

共纳入2135名参与者。约26.0%的人表示他们从未听说过RSV(556/2135),并且不知道婴幼儿感染RSV的风险很高(557/2135)。1岁以下儿童的家长中不知道RSV的比例明显高于其他年龄组儿童的家长。42.9%的家长(916/2135)对自己孩子感染RSV的易感性认知水平较低。70.6%的家长(1508/2135)表示愿意为孩子接种RSV疫苗。拒绝RSV疫苗最常见的原因是“担心疫苗的安全性或副作用”。60.8%的参与者(1299/2135)认为RSV疫苗价格低于200元人民币(28美元)是可以接受的。

结论

家长,尤其是那些孩子较小的家长,对RSV感染的认知和了解有限。我们的研究还表明疫苗价格可能成为未来中国RSV疫苗使用的障碍。

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