Department of Physical Education, Farhangian University, Tehran, Iran.
Department of Psychology, Kermanshah Branch, Islamic Azad University, Kermanshah, Iran.
Arch Psychiatr Nurs. 2024 Dec;53:215-223. doi: 10.1016/j.apnu.2024.10.020. Epub 2024 Oct 17.
Non-pharmacological interventions are available to improve sleep quality including mindfulness-based stress reduction (MBSR) and physical activity (PA). The present study aimed to evaluate the effectiveness of the combination of MBSR and PA interventions as an augmentation to treatment as usual with sertraline to improve sleep and psychological factors among patients with MDD. Sixty-seven patients in outpatient care diagnosed with MDD for a minimum of 2 months (mean age: 35.32 ± 7.8; 65 % female) and currently on sertraline treatments were randomized into four groups including: 1) Physical activity, 2) MBSR, 3) Combination MBSR and physical activity (MBSRPA), and 4) Control. All participants completed self-reported questionnaires on sleep quality, depression, anxiety, and perceived stress from baseline to 8 weeks later at post-test and four weeks later at follow-up. Over time, sleep disturbance and psychological problems were reduced in all conditions when compared to the control. Moreover, MBSRPA had a more positive impacts on perceived stress, anxiety, depressive symptoms and sleep quality. The results of the present study confirmed the effectiveness of MBSRPA as an augmentation to standard therapy to help reduce symptoms of depression, anxiety, perceived stress, and sleep problems in patients with MDD.
非药物干预措施可用于改善睡眠质量，包括正念减压（MBSR）和身体活动（PA）。本研究旨在评估 MBSR 和 PA 干预措施相结合作为常规治疗（舍曲林）的附加治疗，以改善 MDD 患者的睡眠和心理因素。67 名在门诊接受至少 2 个月（平均年龄：35.32±7.8；65%为女性）MDD 诊断且目前正在服用舍曲林治疗的患者被随机分为四组：1）身体活动，2）MBSR，3）MBSR 和身体活动相结合（MBSRPA），以及 4）对照组。所有参与者在基线时完成了睡眠质量、抑郁、焦虑和压力感知的自我报告问卷，然后在 8 周后的测试和 4 周后的随访时完成。随着时间的推移，与对照组相比，所有条件下的睡眠障碍和心理问题都有所减少。此外，MBSRPA 对压力感知、焦虑、抑郁症状和睡眠质量有更积极的影响。本研究结果证实了 MBSRPA 作为常规治疗的附加治疗的有效性，可帮助减少 MDD 患者的抑郁、焦虑、压力感知和睡眠问题症状。
