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[动脉粥样硬化危险因素在人类主动脉粥样硬化前期病变发展中的意义]

[Significance of atherosclerotic risk factors in the development of preatherosclerotic changes in the human aorta].

作者信息

Malaia L T, Kondakov I K, Lazareva S A, Simirenko L L, Bondar' T K

出版信息

Ter Arkh. 1986;58(1):29-33.

PMID:3961688
Abstract

A study of the effect of the main risk factors of atherosclerosis in coronary patients on the prevalence of lipoidosis and prelipid changes in the aortal intima showed a week interrelationship between the studied risk factors and prevalence of lipoidosis. A noticeable significant interrelationship of the prevalence of prelipid changes in the aortal intima, patient's age, the IRI level and alpha-XC concentration in the blood plasma was established. An equation was described. A nomogram was presented permitting determination of the prevalence of prelipid changes in the aortal intima and, consequently, the phase of a course of atherosclerosis during the patient's lifetime on the basis of the above risk factors.

摘要

一项关于冠心病患者动脉粥样硬化主要危险因素对脂样变性患病率及主动脉内膜脂质前期变化影响的研究表明,所研究的危险因素与脂样变性患病率之间存在微弱的相互关系。研究确定了主动脉内膜脂质前期变化的患病率、患者年龄、IRI水平及血浆中α-XC浓度之间存在显著的明显相互关系。描述了一个方程。给出了一个列线图,可根据上述危险因素确定主动脉内膜脂质前期变化的患病率,从而确定患者一生中动脉粥样硬化病程的阶段。

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