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在一名表现为下壁心肌梗死的患者中意外发现主动脉瓣乳头状纤维弹性瘤。

Accidentally Discovered Aortic Valve Papillary Fibroelastoma in a Patient Presenting With Inferior Myocardial Infarction.

作者信息

A Ismaiel Mahmoud, Salah Shehata Mohamed, Khaleel Taha Attaa, Elagha Abdalla

机构信息

Cardiovascular Medicine/Cardiology, Global Medical City Hospital, Cairo, EGY.

Cardiology, College of Medicine, Kasr Alainy University, Cairo, EGY.

出版信息

Cureus. 2024 Oct 31;16(10):e72783. doi: 10.7759/cureus.72783. eCollection 2024 Oct.

DOI:10.7759/cureus.72783
PMID:39618652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11608093/
Abstract

Papillary fibroelastomas (PFEs) are rare, benign primary cardiac tumors. Their clinical manifestations range from asymptomatic findings to serious embolic events, including cerebrovascular accidents, myocardial infarctions, or arrhythmias. Though extremely rare, PFEs have been associated with acute coronary syndrome in only a few cases documented in medical literature. We present the case of a 39-year-old male who presented with acute-onset severe chest pain and was diagnosed with inferior myocardial infarction. Coronary angiography revealed a high thrombus burden in the right coronary artery. Multimodality imaging, including transthoracic echocardiography and cardiac magnetic resonance imaging, identified a well-defined, mobile mass attached to the right coronary cusp of the aortic valve, highly suggestive of a PFE. Following a multidisciplinary consultation, we performed surgical excision of the mass, and histopathology confirmed the diagnosis of PFE. The patient made an uneventful recovery postoperatively. This case highlights the rare association of a PFE with acute coronary syndrome, emphasizing the importance of multimodality imaging in the accurate diagnosis of cardiac masses. Given the potential for serious embolic complications, prompt surgical intervention remains the treatment of choice in symptomatic cases. Further studies are needed to establish clear guidelines for the management of asymptomatic fibroelastomas.

摘要

乳头状纤维弹性瘤(PFEs)是罕见的原发性心脏良性肿瘤。其临床表现多样,从无症状到严重的栓塞事件,包括脑血管意外、心肌梗死或心律失常。虽然极为罕见,但在医学文献记载的少数病例中,PFEs与急性冠状动脉综合征有关。我们报告一例39岁男性,因急性发作的严重胸痛就诊,诊断为下壁心肌梗死。冠状动脉造影显示右冠状动脉血栓负荷高。包括经胸超声心动图和心脏磁共振成像在内的多模态成像发现一个边界清晰、可移动的肿块附着于主动脉瓣右冠状动脉瓣叶,高度提示为PFEs。经过多学科会诊,我们对肿块进行了手术切除,组织病理学确诊为PFEs。患者术后恢复顺利。该病例突出了PFEs与急性冠状动脉综合征的罕见关联,强调了多模态成像在心脏肿块准确诊断中的重要性。鉴于存在严重栓塞并发症的可能性,对于有症状的病例,及时手术干预仍是首选治疗方法。需要进一步研究以建立无症状纤维弹性瘤管理的明确指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/521b0243f263/cureus-0016-00000072783-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/23b3e5a0c9ad/cureus-0016-00000072783-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/6c1493ccbc01/cureus-0016-00000072783-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/9538e3e21583/cureus-0016-00000072783-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/c23dab330359/cureus-0016-00000072783-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/8b3ce0b7b3e1/cureus-0016-00000072783-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/521b0243f263/cureus-0016-00000072783-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/23b3e5a0c9ad/cureus-0016-00000072783-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/6c1493ccbc01/cureus-0016-00000072783-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/9538e3e21583/cureus-0016-00000072783-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/c23dab330359/cureus-0016-00000072783-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/8b3ce0b7b3e1/cureus-0016-00000072783-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e33/11608093/521b0243f263/cureus-0016-00000072783-i06.jpg

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本文引用的文献

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Cardiac papillary fibroelastoma: a rare cause of ST-segment elevation myocardial infarction: a case report.心脏乳头肌纤维弹性瘤:ST段抬高型心肌梗死的罕见病因:一例报告
Ann Med Surg (Lond). 2023 Oct 2;85(11):5800-5803. doi: 10.1097/MS9.0000000000001371. eCollection 2023 Nov.
2
A Case of Papillary Fibroelastoma of the Aortic Valve Causing an Embolic Ischemic Stroke.一例主动脉瓣乳头状纤维弹性瘤导致栓塞性缺血性中风
Cureus. 2022 Aug 20;14(8):e28208. doi: 10.7759/cureus.28208. eCollection 2022 Aug.
3
Papillary fibroelastoma revealed by an acute coronary syndrome with transient ST segment elevation: a case report.
因急性冠状动脉综合征伴短暂 ST 段抬高而显现的心脏乳头状弹力纤维瘤:病例报告。
Pan Afr Med J. 2022 Mar 14;41:206. doi: 10.11604/pamj.2022.41.206.33077. eCollection 2022.
4
Cardiac papillary fibroelastoma.心脏乳头肌纤维弹性瘤
J Geriatr Cardiol. 2021 May 28;18(5):346-351. doi: 10.11909/j.issn.1671-5411.2021.05.009.
5
Cardiac Masses: The Role of Cardiovascular Imaging in the Differential Diagnosis.心脏肿物:心血管成像在鉴别诊断中的作用
Diagnostics (Basel). 2020 Dec 14;10(12):1088. doi: 10.3390/diagnostics10121088.
6
Cardiac Tumors: Diagnosis, Prognosis, and Treatment.心脏肿瘤:诊断、预后和治疗。
Curr Cardiol Rep. 2020 Oct 10;22(12):169. doi: 10.1007/s11886-020-01420-z.
7
Cardiac papillary fibroelastoma originating from the coumadin ridge and review of literature.起源于华法令嵴的心脏乳头状纤维弹性瘤及文献复习。
BMJ Case Rep. 2020 Aug 26;13(8):e235361. doi: 10.1136/bcr-2020-235361.
8
Papillary fibroelastoma of the aortic valve: analysis of 21 cases, including a presentation with cardiac arrest.主动脉瓣乳头状纤维弹性瘤:21例分析,包括1例以心脏骤停为表现的病例。
Tex Heart Inst J. 2015 Apr 1;42(2):131-5. doi: 10.14503/THIJ-14-4262. eCollection 2015 Apr.
9
Images in cardiovascular medicine. Papillary fibroelastoma of the aortic valve: appearance in 64-slice spiral computed tomography, magnetic resonance imaging, and echocardiography.
Circulation. 2007 Jan 2;115(1):e3-6. doi: 10.1161/CIRCULATIONAHA.106.637132.
10
Surgical treatment of cardiac papillary fibroelastoma: a single center experience with eighty-eight patients.心脏乳头状纤维弹性瘤的外科治疗:单中心88例患者的经验
Ann Thorac Surg. 2005 Nov;80(5):1712-8. doi: 10.1016/j.athoracsur.2005.04.030.