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临床静止型皮肌炎中的进行性间质性肺疾病

Progressive Interstitial Lung Disease in a Clinically Quiescent Dermatomyositis.

作者信息

Lomanta Jan Michael Jesse C, Quinto Milraam L, Urquiza Sheen C, Cruz-Bermudez Charito, Santiaguel Joel M

机构信息

Division of Pulmonary Medicine, Philippine General Hospital, University of the Philippines Manila.

Department of Medicine, St. Luke's Medical Center, Bonifacio Global City.

出版信息

Acta Med Philipp. 2023 Apr 28;57(4):68-72. doi: 10.47895/amp.vi0.4693. eCollection 2023.

Abstract

A 60-year-old Filipino woman diagnosed with dermatomyositis was initially on prednisone and methotrexate. She eventually developed interstitial lung disease (ILD) and so methotrexate was shifted to azathioprine; however, azathioprine was discontinued due to cutaneous tuberculosis. Over eight years, the dermatomyositis was controlled by prednisone alone but the ILD worsened. This case demonstrated that the course of ILD may be independent of dermatomyositis.

摘要

一名60岁被诊断为皮肌炎的菲律宾女性最初接受泼尼松和甲氨蝶呤治疗。她最终发展为间质性肺病(ILD),因此甲氨蝶呤换成了硫唑嘌呤;然而,由于皮肤结核,硫唑嘌呤停药。八年来,皮肌炎仅靠泼尼松得到控制,但ILD病情恶化。该病例表明,ILD的病程可能与皮肌炎无关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2365/11603087/8eb88307724f/AMP-57-4-4693-g001.jpg

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