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脑与心脏:左侧感染性心内膜炎合并神经系统并发症时治疗的优先级

Brain vs Heart: Prioritizing Treatment in Left-Side Infective Endocarditis With Neurologic Complications.

作者信息

Rizzo Martina, Cameli Matteo, Marianello Daniele, Franchi Federico, Andriani Stefano, Lorusso Roberto, Montesi Gianfranco, Gelsomino Sandro

机构信息

Department of Cardiothoracic Surgery, School for Cardiovascular Disease, Maastricht University, Maastricht, the Netherlands.

Cardiac Surgery Unit, Cardiothoracic and Vascular Disease Department, Santa Maria Alle Scotte Hospital, University of Siena, Siena, Italy.

出版信息

JACC Case Rep. 2024 Nov 6;29(21):102697. doi: 10.1016/j.jaccas.2024.102697.

DOI:10.1016/j.jaccas.2024.102697
PMID:39619044
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11602588/
Abstract

A paradigmatic case is presented of subarachnoid hemorrhage as the initial sign of bacterial endocarditis on a mechanical cardiac prosthesis, in the absence of symptoms and echocardiographic evidence of infective endocarditis and vegetation. The presentation emphasizes the need to pursue a diagnostic workup for bacterial endocarditis whenever a patient with a mechanical prosthesis presents to the emergency department with focal neurologic signs. In addition, it highlights the potential use of second-level diagnostic tools to assess the extent of abscess presence and lesion extension to other cardiac structures for proper surgical planning. Finally, the presented case confirms that cardiopulmonary bypass surgery is not contraindicated and should not be delayed, even in the presence of extensive endocardial lesions with concurrent subarachnoid hemorrhage.

摘要

本文呈现了一个典型病例,一名接受机械心脏瓣膜置换术的患者,以蛛网膜下腔出血作为细菌性心内膜炎的初始症状,且当时并无感染性心内膜炎及赘生物的症状和超声心动图证据。该病例表明,每当有机械瓣膜置换史的患者因局灶性神经体征就诊于急诊科时,都有必要对细菌性心内膜炎进行诊断性检查。此外,它还强调了使用二级诊断工具评估脓肿范围以及病变向其他心脏结构扩展情况对于进行恰当手术规划的潜在作用。最后,该病例证实,即使存在广泛的心内膜病变并发蛛网膜下腔出血,体外循环手术也并非禁忌,不应延迟进行。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/a69954a1c86e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/bd5dc9a17610/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/989514e19d0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/0a79e614bab0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/38223037bc27/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/824392317b0d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/a69954a1c86e/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/bd5dc9a17610/ga1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/989514e19d0b/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/0a79e614bab0/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/38223037bc27/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/824392317b0d/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6fab/11602588/a69954a1c86e/gr5.jpg

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本文引用的文献

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Correction to: 2023 ESC Guidelines for the management of endocarditis: Developed by the task force on the management of endocarditis of the European Society of Cardiology (ESC) Endorsed by the European Association for Cardio-Thoracic Surgery (EACTS) and the European Association of Nuclear Medicine (EANM).勘误:《2023 欧洲心脏病学会感染性心内膜炎管理指南》:由欧洲心脏病学会(ESC)感染性心内膜炎管理特别工作组制定,得到欧洲心胸外科学会(EACTS)和欧洲核医学协会(EANM)认可。
Eur Heart J. 2023 Dec 1;44(45):4780. doi: 10.1093/eurheartj/ehad625.
2
The Use of the Cryopreserved Aortic Homograft for Aortic Valve Replacement: Is It Still an Option?冷冻保存的主动脉同种异体移植物用于主动脉瓣置换:它仍然是一种选择吗?
J Cardiovasc Dev Dis. 2023 Jun 8;10(6):248. doi: 10.3390/jcdd10060248.
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Infective endocarditis and stroke: when does it bleed? A single center retrospective study.感染性心内膜炎与卒中:何时会出血?一项单中心回顾性研究。
Neurol Res Pract. 2023 Apr 6;5(1):13. doi: 10.1186/s42466-023-00239-7.
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Cryopreserved aortic homografts for complex aortic valve or root endocarditis: a 28-year experience.冷冻保存的同种主动脉移植物治疗复杂主动脉瓣或根部心内膜炎:28 年经验。
Eur J Cardiothorac Surg. 2022 Aug 3;62(3). doi: 10.1093/ejcts/ezac193.
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2020 ACC/AHA Guideline for the Management of Patients With Valvular Heart Disease: Executive Summary: A Report of the American College of Cardiology/American Heart Association Joint Committee on Clinical Practice Guidelines.2020 ACC/AHA 瓣膜性心脏病患者管理指南:执行摘要:美国心脏病学会/美国心脏协会临床实践指南联合委员会的报告。
J Am Coll Cardiol. 2021 Feb 2;77(4):450-500. doi: 10.1016/j.jacc.2020.11.035. Epub 2020 Dec 17.
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Intracranial haemorrhage in infective endocarditis.感染性心内膜炎所致的颅内出血。
Arch Cardiovasc Dis. 2018 Dec;111(12):712-721. doi: 10.1016/j.acvd.2018.03.009. Epub 2018 Jun 5.
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