Alshurafa Haider A, Altoukhi Khalid H, Alhassan Bassam F, Alshehri Mohammed A, Aldhaheri Ruba H, Tawffeq Abdulaziz M
Hepatopancreatobiliary, General Surgery Consultant, General Surgery Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Surgical Oncology, General surgery consultant, General Surgery Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Int J Surg Case Rep. 2025 Jan;126:110650. doi: 10.1016/j.ijscr.2024.110650. Epub 2024 Nov 23.
Incidental neoplastic findings after routine cholecystectomy are becoming more common. However, low-grade dysplasia at the cystic duct resection margin remains rare and lacks established management guidelines.
A 37-year-old male underwent a routine laparoscopic cholecystectomy. Subsequent histology revealed low-grade dysplasia and intestinal metaplasia at the resected cystic duct margin. A laparoscopic resection of the cystic duct stump up to its junction with the common bile duct was performed, resulting in an uneventful recovery. Post-operative histological examination confirmed the absence of dysplasia at the new cystic margins.
The management of low-grade dysplasia at the cystic duct margin is challenging due to its rarity and the lack of standardized treatment protocols. Our case demonstrates the feasibility and potential benefits of surgical intervention in such scenarios.
Resection of the remaining cystic stump with confirmation of negative margins appears to be an optimal treatment for low-grade dysplasia at the cystic duct margin. However, further studies are necessary to evaluate the roles of surgery and surveillance in managing this rare condition.
常规胆囊切除术后偶然发现肿瘤性病变的情况越来越常见。然而,胆囊管切缘的低级别发育异常仍然罕见,且缺乏既定的管理指南。
一名37岁男性接受了常规腹腔镜胆囊切除术。随后的组织学检查显示,切除的胆囊管切缘存在低级别发育异常和肠化生。对胆囊管残端直至其与胆总管交界处进行了腹腔镜切除,术后恢复顺利。术后组织学检查证实新的胆囊切缘无发育异常。
由于胆囊管切缘低级别发育异常罕见且缺乏标准化治疗方案,其管理具有挑战性。我们的病例证明了在这种情况下手术干预的可行性和潜在益处。
切除剩余胆囊残端并确认切缘阴性似乎是胆囊管切缘低级别发育异常的最佳治疗方法。然而,需要进一步研究来评估手术和监测在管理这种罕见疾病中的作用。