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小儿肥胖对开放及腹腔镜阑尾切除术结局的影响。

Pediatric Obesity's Effect on Open and Laparoscopic Appendectomy Outcomes.

作者信息

Bhatnagar Anshul, Nigam Nishtha, Anne Rohan, Santosh Sadashiv

机构信息

School of Medicine, Baylor College of Medicine, Houston, Texas.

Department of Internal Medicine, Monmouth Medical Center, Long Branch, NJ.

出版信息

Surg J (N Y). 2024 Oct 24;10(4):e37-e42. doi: 10.1055/s-0044-1791968. eCollection 2024 Oct.

Abstract

Pediatric obesity is a common comorbid condition that may complicate pediatric surgeries, such as appendectomy. Prior research on the consequences of obesity on pediatric appendectomy outcomes have been limited by small-sample sizes and pooled analyses that do not distinguish the effects of surgical approach. Associations between surgical approach, pediatric obesity, and postoperative appendectomy outcomes thus remain unclear.  To analyze postoperative appendectomy outcomes by accounting for pediatric obesity, appendectomy approach, and their interaction. This is a retrospective cohort population analysis. Nationwide data of pediatric inpatients from the United States were obtained. All pediatric patients who had an appendectomy were selected from the 2019 Kids' Inpatient Database.  Outcomes variables were the length of stay and postoperative complication rate. The primary exposure variables were pediatric obesity, surgical approach (laparoscopic [LA] vs. open appendectomy [OA]), and an interaction term between the two. Control variables were patient demographics, clinical complexity, and geographic location. Multiple regression was used to determine relationships between the outcome, exposure, and control variables.  A total of 49,037 pediatric patients had an appendectomy, with the number of OA and LA being 4,517 and 44,420, respectively. LA patients had 5.8% (  < 0.001) shorter length of stay than OA patients. For obese patients, length of stay was 31.8% (  < 0.001) longer than for nonobese patients, but LA (compared with OA) reduced it by 19% (  < 0.007). Obesity had no effect on the number of postoperative complications.  Obese patients had significantly longer length of stay than nonobese counterparts following OA (31.8%), but this difference was minimized for LA patients (15.81%). There was no association between complication rate, obesity, and surgical approach. Our findings will enable more accurate estimations of pediatric patients' postoperative courses and efficient allocation of limited hospital resources. Further research may wish to study the effects of other common pediatric comorbidities on other procedures.

摘要

小儿肥胖是一种常见的合并症,可能会使小儿外科手术(如阑尾切除术)复杂化。先前关于肥胖对小儿阑尾切除术后结果影响的研究因样本量小和汇总分析未区分手术方式的影响而受到限制。因此,手术方式、小儿肥胖与阑尾切除术后结果之间的关联仍不明确。

为了通过考虑小儿肥胖、阑尾切除手术方式及其相互作用来分析阑尾切除术后的结果。这是一项回顾性队列人群分析。获取了来自美国的全国小儿住院患者数据。所有接受阑尾切除术的小儿患者均选自2019年儿童住院数据库。

结果变量为住院时间和术后并发症发生率。主要暴露变量为小儿肥胖、手术方式(腹腔镜手术[LA]与开放性阑尾切除术[OA])以及两者之间的交互项。控制变量为患者人口统计学特征、临床复杂性和地理位置。采用多元回归来确定结果、暴露和控制变量之间的关系。

共有49,037名小儿患者接受了阑尾切除术,其中OA和LA的数量分别为4,517例和44,420例。LA患者的住院时间比OA患者短5.8%(P<0.001)。对于肥胖患者,住院时间比非肥胖患者长31.8%(P<0.001),但LA(与OA相比)使其缩短了19%(P<0.007)。肥胖对术后并发症数量没有影响。

肥胖患者在接受OA后的住院时间明显长于非肥胖患者(31.8%),但LA患者的这种差异最小化(15.81%)。并发症发生率、肥胖与手术方式之间没有关联。我们的研究结果将有助于更准确地估计小儿患者的术后病程,并有效分配有限的医院资源。进一步的研究可能希望探讨其他常见小儿合并症对其他手术的影响。

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