Kundu Aditya, Ghosh Nirmalya, Sengupta Mallika, Chatterjee Shiv Sekhar
Department of Microbiology, All India Institute of Medical Sciences, Kalyani, India.
Department of Urology, All India Institute of Medical Sciences, Kalyani, India.
Case Rep Nephrol Dial. 2024 Dec 3;14(1):185-189. doi: 10.1159/000542203. eCollection 2024 Jan-Dec.
species other than are being continuously reported as pathogens.
A patient visited the Urology Outpatient Department of a tertiary care centre in India reporting lower abdominal pain, urinary incontinence, and intermittent weak urine flow persisting for 12 years, intensifying over the last 15 days. She also experienced urgency, straining, weak stream, and incomplete voiding, along with a previous fever episode. The patient had a medical record of multiple urethral dilations and surgeries since 2014, with the most recent urethral dilatation in July 2023. Diagnostic tests revealed a thickened bladder with notable post-void residual urine. Uroflowmetry indicated obstructive uropathy. Urine analysis exhibited elevated leucocytes, epithelial cells, red blood cells, and abundant bacilli. was identified through matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS) following three pure growths of Gram-positive bacilli in urine cultures. The organism showed sensitivity to cotrimoxazole and tetracyclines. Treatment with doxycycline significantly improved the symptoms.
The organism is a very rare cause of UTI and the patient responded well to treatment.
除了[具体物种未提及]之外，其他物种不断被报告为病原体。
一名患者前往印度一家三级护理中心的泌尿外科门诊就诊，报告下腹部疼痛、尿失禁和间歇性弱尿流持续12年，在过去15天内加重。她还经历了尿急、用力排尿、尿流变弱和排尿不完全，以及之前的发热发作。自2014年以来，该患者有多次尿道扩张和手术的病史，最近一次尿道扩张是在2023年7月。诊断测试显示膀胱增厚，有明显的排尿后残余尿。尿流率测定表明存在梗阻性尿路病。尿液分析显示白细胞、上皮细胞、红细胞升高，并有大量杆菌。在尿液培养中革兰氏阳性杆菌三次纯培养后，通过基质辅助激光解吸电离飞行时间质谱（MALDI-TOF MS）鉴定出[具体物种未提及]。该生物体对复方新诺明和四环素敏感。用强力霉素治疗显著改善了症状。
[具体物种未提及]生物体是尿路感染的一种非常罕见的病因，患者对治疗反应良好。
