Patil Parag, Kusneniwar Govindrao, Rathod Gunvanti, Pradeep Immanuel, Prabhala Shailaja, Pyati Anand, Rani Komal, Katyal Sakshi, Chada Tejaswi
Department of Pathology and Laboratory Medicine, AIIMS, Hyderabad, Telangana, India.
Department of Community Medicine and Family Medicine, AIIMS, Hyderabad, Telangana, India.
J Family Med Prim Care. 2024 Oct;13(10):4611-4615. doi: 10.4103/jfmpc.jfmpc_553_24. Epub 2024 Oct 18.
This study aimed to estimate the prevalence of anaemia and haemoglobinopathies, particularly beta-thalassemia in the tribal population of the Yadadri-Bhuvanagiri district of Telangana.
The sample consisted of a tribal population (Banjara) that visited voluntary blood camps set up in tribal settlements, local schools, and the Gram-panchayat office, in collaboration with local healthcare workers. Haemoglobin measurements (Anaemia) and Mentzer index of whole blood (EDTA) samples were used as diagnostic screening tools for categorising the population at risk of beta-thalassemia. HPLC was used as a confirmatory test.
The study included a total of = 479 (68% females and 32% males) voluntary adult participants of Banjara. Based on the haemoglobin levels, 105 females (32%) were found to be anaemic as compared to 24 males (15.5%). Among the female population, a small percentage of individuals had severe anaemia (1.9%), while most had mild (80%) or moderate anaemia (18%); on the other hand, males primarily had moderate anaemia. Out of the total screened population, 6.7% (5.2% with low Hb levels (anaemic), 3.3% by MI) were found to be thalassemia based on anaemia and Mentzer index as a screening tool.
The prevalence of beta-thalassemia was found 6.7% in the Banjara population.
本研究旨在估计印度特伦甘纳邦亚达德里-布瓦纳吉里区部落人口中贫血和血红蛋白病,特别是β地中海贫血的患病率。
样本包括一个部落人口(班贾拉人),他们与当地医护人员合作,前往在部落定居点、当地学校和村委会办公室设立的自愿献血营地。血红蛋白测量(贫血)和全血(乙二胺四乙酸)样本的门泽尔指数被用作诊断筛查工具,以对有β地中海贫血风险的人群进行分类。高效液相色谱法用作确证试验。
该研究共纳入了479名(68%为女性,32%为男性)自愿参与的成年班贾拉人。根据血红蛋白水平,发现105名女性(32%)贫血,而男性为24名(15.5%)。在女性人群中,一小部分个体患有严重贫血(1.9%),而大多数患有轻度贫血(80%)或中度贫血(18%);另一方面,男性主要患有中度贫血。在全部筛查人群中,基于贫血和门泽尔指数作为筛查工具,发现6.7%(血红蛋白水平低(贫血)的占5.2%,门泽尔指数筛查的占3.3%)为地中海贫血。
在班贾拉人群中发现β地中海贫血的患病率为6.7%。