Chirande Lulu, Namazzi Ruth, Hockenberry Marilyn, Wasswa Peter, Kiguli Sarah, Mulemba Tadala, Gastier-Foster Julie M, Lyimo Magdalena, Airewele Gladstone, Lubega Joseph, Ozuah Nmazuo
Department of Pediatrics, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.
Department of Pediatrics and Child Health, Makerere University College of Health Sciences, Kampala, Uganda.
Blood Adv. 2025 Feb 25;9(4):939-947. doi: 10.1182/bloodadvances.2024012983.
The spectrum of hematological diseases in African children includes anemias, bleeding disorders, thromboses, and oncological diseases such as leukemias. Although data are limited, outcomes for these diseases are poorer in Africa. The dearth of specialists, and lack of infrastructure that supports diagnosis and management, have been identified as key barriers to improving outcomes for childhood hematological disorders in Sub-Saharan Africa (SSA). To address these, intentional capacity building efforts addressing education and training, diagnostic capacity, and access to blood products and medicines are needed. This article explores some ongoing efforts in the region aimed at fostering the capacity to identify and treat childhood hematological disorders across a breadth of initiatives targeting the critical themes of education, diagnostic support, and treatment. We also identify existing opportunities through international partnerships, to build sustainable programs that can support children with hematological diseases in SSA.
非洲儿童的血液疾病谱包括贫血、出血性疾病、血栓形成以及白血病等肿瘤性疾病。尽管数据有限,但这些疾病在非洲的治疗结果较差。专家短缺以及缺乏支持诊断和管理的基础设施,已被确定为改善撒哈拉以南非洲(SSA)儿童血液疾病治疗结果的关键障碍。为解决这些问题,需要有针对性地开展能力建设工作,涵盖教育与培训、诊断能力以及血液制品和药品的获取。本文探讨了该地区目前正在进行的一些努力,这些努力旨在通过一系列针对教育、诊断支持和治疗等关键主题的举措,培养识别和治疗儿童血液疾病的能力。我们还通过国际伙伴关系确定了现有机会,以建立可持续项目,为SSA患有血液疾病的儿童提供支持。