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冻融胚胎移植后先兆流产女性妊娠8周时发生卵巢扭转:一例报告

Ovarian Torsion at 8 weeks of Gestation in a Woman with Threatened Abortion After Frozen-Thawed Embryo Transfer: A Case Report.

作者信息

Ju Wenhan, Zhang Jinfu, Wang Yue, Pan Keying, Zhang Qianwen, Zhao Shuai, Lian Fang

机构信息

Guanghua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

Shenzhen Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shenzhen, People's Republic of China.

出版信息

Int J Womens Health. 2024 Nov 29;16:2043-2050. doi: 10.2147/IJWH.S488657. eCollection 2024.

Abstract

INTRODUCTION

Ovarian torsion during pregnancy is a rare condition that requires prompt diagnosis and repositioning to preserve ovarian function.

CASE REPORT

A 32-year-old woman underwent a successful pregnancy after FET, but was hospitalized for observation because of a threatened abortion. During the 8th week of pregnancy, a transvaginal ultrasound examination was performed due to sudden lower abdominal pain, which displayed an 8.3×5.2cm right ovary and a 4.3×3.6 cm enhanced echogenic mass over the right ovary with striated structures. Consequently, a preliminary diagnosis of ovarian torsion was made, and urgent laparoscopic exploration was conducted. Intraoperatively, the right fallopian tube and right ovary were rotated counterclockwise by 720 degrees. After rotate and reposition the right ovary and fallopian tube, a 3 cm diameter cyst was punctured. After 1 hour of observation, a 2×1×1cm segment of ovarian tissue was excised. Pregnancy was maintained with aggressive postoperative luteal support and anti-infective treatment.

CONCLUSION

The use of clomiphene citrate during endometrium preparation for frozen-thawed embryo transfer cycles may elevate the risk of ovarian torsion. Laparoscopic ovarian repositioning after ovarian torsion in pregnant women, even those with threatened abortion, is safe when combined with postoperative anti-infective treatment and intensive luteal support.

摘要

引言

妊娠期卵巢扭转是一种罕见疾病,需要迅速诊断并复位以保留卵巢功能。

病例报告

一名32岁女性在冻融胚胎移植(FET)后成功妊娠,但因先兆流产住院观察。妊娠第8周时,因突发下腹痛进行经阴道超声检查,显示右侧卵巢大小为8.3×5.2cm,右侧卵巢上方有一4.3×3.6cm的增强回声团块,伴有条纹状结构。因此,初步诊断为卵巢扭转,并进行了紧急腹腔镜探查。术中,右侧输卵管和右侧卵巢逆时针旋转720度。在旋转并重新定位右侧卵巢和输卵管后,穿刺了一个直径3cm的囊肿。观察1小时后,切除了一块2×1×1cm的卵巢组织。术后通过积极的黄体支持和抗感染治疗维持妊娠。

结论

在冻融胚胎移植周期的子宫内膜准备过程中使用枸橼酸氯米芬可能会增加卵巢扭转的风险。对于妊娠期卵巢扭转的孕妇,即使是有先兆流产的孕妇,在术后抗感染治疗和强化黄体支持的情况下,腹腔镜下卵巢复位是安全的。

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