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一例狼疮性脂膜炎所致面部脂肪萎缩经注射透明质酸成功治疗的病例报告。

A case report of lupus panniculitis-induced facial lipoatrophy successfully treated with injectable hyaluronic acid.

作者信息

Green Rebecca, Hardin Jori, Robertson Lynne, Remington Todd

机构信息

Division of Dermatology, University of Calgary, Calgary, AB, Canada.

出版信息

SAGE Open Med Case Rep. 2024 Dec 4;12:2050313X241304879. doi: 10.1177/2050313X241304879. eCollection 2024.

DOI:10.1177/2050313X241304879
PMID:39634072
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11615975/
Abstract

Lupus panniculitis is a chronic subtype of cutaneous lupus erythematosus. It typically presents as tender, firm subcutaneous nodules on the proximal extremities, face, and/or trunk and can leave behind disfiguring scarring or lipoatrophy in the post-inflammatory phase. When a patient presents with physical or emotional distress secondary to lupus panniculitis-induced lipoatrophy, there are variable data on treatment with autologous fat transfer and injectable fillers. We present the case of a 37-year-old female presenting with lipoatrophy of the right cheek, after 2 years of quiescent disease, undergoing successful volume restoration with injectable hyaluronic acid filler.

摘要

狼疮性脂膜炎是皮肤红斑狼疮的一种慢性亚型。它通常表现为近端肢体、面部和/或躯干上出现压痛性、坚实的皮下结节,在炎症后期可留下毁容性瘢痕或脂肪萎缩。当患者因狼疮性脂膜炎引起的脂肪萎缩而出现身体或情绪困扰时,关于自体脂肪移植和可注射填充剂治疗的数据不一。我们报告一例37岁女性病例,该患者在病情静止2年后出现右脸颊脂肪萎缩,通过注射透明质酸填充剂成功恢复了容积。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544e/11615975/f2fffe599356/10.1177_2050313X241304879-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544e/11615975/923490ea2c74/10.1177_2050313X241304879-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544e/11615975/f2fffe599356/10.1177_2050313X241304879-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544e/11615975/923490ea2c74/10.1177_2050313X241304879-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/544e/11615975/f2fffe599356/10.1177_2050313X241304879-fig2.jpg

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本文引用的文献

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Autologous Fat Transfer in Lupus Panniculitis Facial Lipoatrophy.自体脂肪移植治疗狼疮性脂膜炎面部脂肪萎缩
Arch Plast Surg. 2022 Jul 30;49(4):527-530. doi: 10.1055/s-0042-1751024. eCollection 2022 Jul.
2
Poly-l-Lactic Acid for Treating Facial Lipoatrophy Secondary to Lupus Erythematosus Panniculitis.
Dermatol Surg. 2021 Jun 1;47(6):848-849. doi: 10.1097/DSS.0000000000002716.
3
Refractory lupus panniculitis treated successfully with rituximab: Two cases.利妥昔单抗成功治疗难治性狼疮性脂膜炎:两例报告
Ann Afr Med. 2020 Jul-Sep;19(3):207-210. doi: 10.4103/aam.aam_42_19.
4
Cosmetic treatment in patients with autoimmune connective tissue diseases: Best practices for patients with lupus erythematosus.自身免疫性结缔组织病患者的美容治疗:红斑狼疮患者的最佳实践。
J Am Acad Dermatol. 2020 Aug;83(2):343-363. doi: 10.1016/j.jaad.2020.03.123. Epub 2020 Apr 28.
5
Intravenous Immunoglobulin in the Management of Lupus Erythematosus Panniculitis.静脉注射免疫球蛋白在红斑狼疮性脂膜炎治疗中的应用
Cureus. 2020 Jan 27;12(1):e6790. doi: 10.7759/cureus.6790.
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Evaluation of Repairing Facial Depression Deformities Secondary to Lupus Erythematosus Panniculitis With Autologous Fat Grafting.自体脂肪移植修复狼疮性脂膜炎继发面部凹陷畸形的评估
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Lupus erythematosus panniculitis-induced facial atrophy: effective treatment with poly-L-lactic acid and hyaluronic acid dermal fillers.红斑狼疮性脂膜炎所致面部萎缩:聚左旋乳酸和透明质酸真皮填充剂的有效治疗
J Am Acad Dermatol. 2013 Nov;69(5):e260-e262. doi: 10.1016/j.jaad.2013.06.037.
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Dermatol Surg. 2011 Jan;37(1):111-5. doi: 10.1111/j.1524-4725.2010.01829.x. Epub 2010 Nov 17.