Talebi Nasibeh, Prochnow Astrid, Frings Christian, Münchau Alexander, Mückschel Moritz, Beste Christian
Cognitive Neurophysiology, Department of Child and Adolescent Psychiatry, Faculty of Medicine, TU Dresden, 01309 Dresden, Germany.
Cognitive Psychology, University of Trier, 54269 Trier, Germany.
iScience. 2024 Sep 20;27(10):110995. doi: 10.1016/j.isci.2024.110995. eCollection 2024 Oct 18.
Adaptive behavior is based on flexibly managing and integrating perceptual and motor processes, and the reconfiguration thereof. Such adaptive behavior is also relevant during inhibitory control. Although research has demonstrated local activity modulations in theta and alpha frequency bands during behavioral adaptation, the communication of brain regions is insufficiently studied. Examining directed connectivity between brain regions using a machine learning approach, a generally increased activity, but decreased connectivity within a temporo-occipital theta band network was revealed during the reconfiguration of perception-action associations during inhibitory control. Additionally, a fronto-occipital alpha-theta interplay yielded a decrease in directed connectivity during reconfiguration processes, which was associated with lower error rates in behavior. Thus, adaptive behavior relies on both local increases and decreases of activity depending on the frequency band, and concomitant decreases in communication between frontal and sensory cortices. The findings reframe common conceptualizations about how adaptive behavior is supported by neural processes.
适应性行为基于灵活地管理和整合感知与运动过程及其重新配置。这种适应性行为在抑制控制过程中也很重要。尽管研究已经证明在行为适应过程中theta和alpha频段存在局部活动调制，但大脑区域之间的通信尚未得到充分研究。使用机器学习方法检查大脑区域之间的定向连接性，发现在抑制控制期间感知 - 行动关联重新配置过程中，颞枕theta频段网络内的活动普遍增加，但连接性降低。此外，额枕alpha - theta相互作用在重新配置过程中导致定向连接性下降，这与行为中较低的错误率相关。因此，适应性行为依赖于根据频段的局部活动增加和减少，以及额叶和感觉皮层之间通信的相应减少。这些发现重新构建了关于神经过程如何支持适应性行为的常见概念。
