Suppr超能文献

利用2019年埃塞俄比亚人口与健康调查分析埃塞俄比亚儿童对双价脊髓灰质炎灭活疫苗的接种情况及其影响因素:混合效应模型

Non-uptake of dual protective polio vaccine and its determinants among children in Ethiopia using Ethiopian Demographic Health Survey 2019: a mixed-effect model.

作者信息

Agimas Muluken Chanie, Belew Aysheshim Kassahun, Muhammad Esmael Ali, Tesfie Tigabu Kidie, Bizuayehu Molla Azmeraw, Abate Biruk Beletew, Kassaw Amare

机构信息

Department of Epidemiology and Biostatistics, University of Gondar, Gondar, Ethiopia

Department of Human Nutrition, University of Gondar, Gondar, Ethiopia.

出版信息

BMJ Open. 2024 Aug 31;14(8):e083648. doi: 10.1136/bmjopen-2023-083648.

Abstract

INTRODUCTION

The polio vaccine is the live-attenuated antigen that prevents poliomyelitis. According to a report by the WHO, about 1 million less than 5-year-old children missed the polio vaccination from 2018 to 2021. Even though Ethiopia is the most prioritised country for polio eradication, there is not enough evidence about the combined oral and inactivated vaccine in Ethiopia.

OBJECTIVE

To assess the non-uptake of the dual protective polio vaccine and its determinants among children in Ethiopia using the Ethiopian Demographic Health Survey (EDHS) 2019.

METHODS

The secondary data analysis of a community-based cross-sectional study was conducted using EDHS 2019 data among 3094 participants. Mixed-effects binary logistic regression was used for descriptive analysis and identifying the predictors using a p value of <0.05. Intraclass correlation was used to assess the clustering effect.

RESULTS

The prevalence of non-uptake of the dual protective polio vaccine in Ethiopia was 44% (95% CI 42.2% to 45.8%). Predictors like women with low proportions of community media exposure (adjusted OR (AOR)=2.3, 95% CI 1.8 to 2.8) and no history of antenatal care visits (AOR=2.3, 95% CI 3.89 to 6.35) were significantly associated with non-uptake of the dual protective polio vaccine.

CONCLUSION

The burden of non-uptake of the dual protective polio vaccine in Ethiopia was still high. Low community media exposure and no antenatal care utilisation were the predictors of non-uptake of the dual protective polio vaccine. We recommend improving media access and antenatal care services to expand polio vaccination.

摘要

引言

脊髓灰质炎疫苗是预防脊髓灰质炎的减毒活抗原。根据世界卫生组织的一份报告,2018年至2021年期间,约有100万5岁以下儿童未接种脊髓灰质炎疫苗。尽管埃塞俄比亚是根除脊髓灰质炎的重点国家,但该国关于口服和灭活联合疫苗的证据不足。

目的

利用2019年埃塞俄比亚人口与健康调查(EDHS)评估埃塞俄比亚儿童对双重保护脊髓灰质炎疫苗的未接种情况及其决定因素。

方法

使用2019年EDHS数据对3094名参与者进行基于社区的横断面研究的二次数据分析。采用混合效应二元逻辑回归进行描述性分析,并使用p值<0.05来确定预测因素。使用组内相关性评估聚类效应。

结果

埃塞俄比亚双重保护脊髓灰质炎疫苗未接种率为44%(95%CI 42.2%至45.8%)。社区媒体曝光率低的女性(调整后的比值比(AOR)=2.3,95%CI 1.8至2.8)和无产前检查史(AOR=2.3,95%CI 3.89至6.35)等预测因素与双重保护脊髓灰质炎疫苗未接种显著相关。

结论

埃塞俄比亚双重保护脊髓灰质炎疫苗未接种负担仍然很高。社区媒体曝光率低和未利用产前护理是双重保护脊髓灰质炎疫苗未接种的预测因素。我们建议改善媒体获取和产前护理服务,以扩大脊髓灰质炎疫苗接种。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验