de Silva Arjuna Priyadarsin, Nuwanshika Nilushi, Dassanayake Uditha, Niriella Madunil Anuk, Ranasinghe Poornima, de Silva H Janaka
Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
Expert Rev Gastroenterol Hepatol. 2024 Nov;18(11):745-752. doi: 10.1080/17474124.2024.2438708. Epub 2024 Dec 19.
Diverticular disease, including diverticulosis and diverticulitis, presents a significant health concern globally, with increasing prevalence in Western societies and emerging trends in Asia. The incidence of diverticulitis, is on the rise, leading to significant morbidity and healthcare costs.
A literature search was conducted using the PubMed database, and studies published between 1995 and 2024 were selected based on their relevance to the overall understanding of disease. This review investigates the clinical spectrum, classification, and management strategies of diverticular disease, focusing particularly on evolving trends in diagnosis and treatment. Discussions regarding the prevalence of diverticulosis, the identification of risk factors associated with disease progression, recent advancements in research, and the utilization of biomarkers in disease monitoring and treatment decision-making are considered in detail.
The discourse on diverticular disease underscores the pressing need for tailored management strategies and innovative treatments. Understanding the intricacies of the disease's pathophysiology is paramount for effective intervention. Recent advances in diagnostic imaging and biomarker identification are promising, yet more research is imperative to further refine patient care. Advances in these areas hold the potential for significantly improving outcomes in disease management.
憩室病，包括憩室症和憩室炎，是全球范围内一个重大的健康问题，在西方社会的患病率不断上升，在亚洲也呈现出新的趋势。憩室炎的发病率正在上升，导致了显著的发病率和医疗费用。
使用PubMed数据库进行了文献检索，并根据其与疾病总体理解的相关性，选择了1995年至2024年发表的研究。本综述调查了憩室病的临床谱、分类和管理策略，特别关注诊断和治疗方面不断演变的趋势。详细讨论了憩室症的患病率、与疾病进展相关的危险因素的识别、研究的最新进展以及生物标志物在疾病监测和治疗决策中的应用。
关于憩室病的讨论强调了制定个性化管理策略和创新治疗方法的迫切需求。了解疾病病理生理学的复杂性对于有效干预至关重要。诊断成像和生物标志物识别方面的最新进展很有前景，但还需要更多研究来进一步优化患者护理。这些领域的进展有可能显著改善疾病管理的结果。
