重度抑郁症的精神药理学最新进展
Recent Advances in the Psychopharmacology of Major Depressive Disorder.
作者信息
Alexander Laith, Young Allan H
机构信息
Department of Psychological Medicine, School of Academic Psychiatry, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.
St Thomas' Hospital, London, UK.
出版信息
BJPsych Adv. 2023 Mar;29(2):117-130. doi: 10.1192/bja.2022.14. Epub 2022 Apr 4.
Abstract
This review highlights some of the recent advances in the psychopharmacology of Major Depressive Disorder (MDD). We synthesise evidence on emerging pharmacological therapies targeting the serotonergic system, before exploring several novel treatment targets: the glutamatergic system, the GABAergic system, and inflammation. When describing new treatment avenues, we examine the evidence base and how far these new treatments are from routine practice.
摘要
本综述重点介绍了重度抑郁症（MDD）心理药理学的一些最新进展。在探讨几个新的治疗靶点：谷氨酸能系统、γ-氨基丁酸能系统和炎症之前，我们综合了针对血清素能系统的新兴药物治疗的证据。在描述新的治疗途径时，我们审视了证据基础以及这些新治疗方法距离常规临床应用还有多远。
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