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2019冠状病毒病与高血糖水平相关:严重急性呼吸综合征冠状病毒2大流行期间的糖尿病性神经病变:一例病例报告

COVID-19 is associated with high blood glucose levels: diabetic neuropathy during the SARS-CoV-2 pandemic: a case report.

作者信息

Bereda Gudisa

机构信息

Pharmacy Department, All Africa Leprosy, Tuberculosis and Rehabilitation Training Centre, Zenebework, Kolfe Keranio, Addis Ababa, Ethiopia.

出版信息

Ann Med Surg (Lond). 2024 Oct 30;86(12):7318-7321. doi: 10.1097/MS9.0000000000000990. eCollection 2024 Dec.

Abstract

INTRODUCTION AND IMPORTANCE

The nerves in the legs and feet are most frequently damaged by diabetic neuropathy. The COVID-19 infection is associated with a high risk of neuropathy symptoms.

CASE PRESENTATION

On 12 July 2022, a 58-year-old black female retiree with significant symptoms of numbness and muscle weakness in the hands and legs was brought into the emergency room. Seventeen years prior, she was diagnosed with type 2 diabetes mellitus. Metformin 1.5 g twice a day and glibenclamide 10 mg twice a day were part of her therapy regimen. When she was admitted to the emergency room, she described a one-day history of shortness of breath, frequent urination, excessive thirst, hyperglycemia, excessive appetite, fever, headache, and dehydration. A chest radiograph showed bilateral diffuse, patchy airspace opacities that could be caused by multifocal pneumonia or viral pneumonia. She started receiving 1000 ml of fluid resuscitation (0.9% normal saline) as soon as she was moved to an ICU, along with a drip-in insulin infusion.

CLINICAL DISCUSSION

Diabetes, infections like COVID-19, poor vitamin levels, and other factors can all contribute to diabetic neuropathies. According to the Centers for Disease Control and Prevention, patients with type 2 diabetes mellitus are much more likely to experience severe morbidity and death from coronavirus disease.

CONCLUSION

Symptoms of diabetic neuropathy continued for months after a COVID-19 infection test resulted in a positive result.

摘要

引言与重要性

腿部和足部的神经最常因糖尿病神经病变而受损。新型冠状病毒肺炎(COVID-19)感染与神经病变症状的高风险相关。

病例介绍

2022年7月12日,一名58岁的黑人女性退休人员因手部和腿部出现明显的麻木和肌肉无力症状被送入急诊室。17年前,她被诊断出患有2型糖尿病。她的治疗方案包括每天两次服用1.5克二甲双胍和每天两次服用10毫克格列本脲。当她被送往急诊室时,她描述了一天的呼吸急促、尿频、口渴、高血糖、食欲亢进、发热、头痛和脱水病史。胸部X光片显示双侧弥漫性、斑片状气腔混浊,可能由多灶性肺炎或病毒性肺炎引起。她一被转移到重症监护病房就开始接受1000毫升的液体复苏(0.9%生理盐水),同时静脉滴注胰岛素。

临床讨论

糖尿病、COVID-19等感染、维生素水平低下以及其他因素都可能导致糖尿病神经病变。根据疾病控制与预防中心的数据,2型糖尿病患者因冠状病毒病出现严重发病和死亡的可能性要高得多。

结论

COVID-19感染检测呈阳性后,糖尿病神经病变的症状持续了数月。

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本文引用的文献

5
Diabetes Mellitus and COVID-19: Review Article.糖尿病与 COVID-19:综述文章。
Diabetes Metab Syndr. 2021 Nov-Dec;15(6):102268. doi: 10.1016/j.dsx.2021.102268. Epub 2021 Sep 4.

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