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2型糖尿病患者嗅觉功能障碍的危险因素

Risk Factors for Olfactory Dysfunction in Patients with Type 2 Diabetes Mellitus.

作者信息

Sani Benny Mart, Rambe Andrina Yunita Murni, Yudhistira Ashri, Nursiah Siti, Harahap M Pahala Hanafi, Ashar Taufik

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, Faculty of Medicine, Universitas Sumatera Utara, Jl. Dr. Mansur No. 5, Medan, 20155, INDONESIA.

Faculty of Public Health, Universitas Sumatera Utara, Jl. Universitas No. 21, Medan, 20155, INDONESIA.

出版信息

Iran J Otorhinolaryngol. 2024;36(6):655-661. doi: 10.22038/ijorl.2024.78347.3647.

Abstract

INTRODUCTION

Patients with type 2 Diabetes Mellitus (DM) often experience olfactory dysfunction; however, the relationship between disease duration and comorbidities remains unclear.

MATERIALS AND METHODS

An analytical observational study was conducted at the Endocrinology and Metabolic Polyclinicof the H. Adam Malik General Hospital, Medan. The study included 66 patients with type 2 DM who met the inclusion criteria. Data were collected from medical records, questionnaires, routine ENT examinations, and the Sniffin' Sticks Test (<0.05).

RESULTS

No significant relationship was observed between sex and olfactory function in patients with type 2 DM. However, a significant correlation was observed between age and the olfactory function score ( = 0.012) as well as between the duration of type 2 DM and the olfactory function score (= 0.005). There was no significant difference in olfactory function scores between patients with type 2 DM with and without comorbidities.

CONCLUSIONS

This study revealed that increasing age and the duration of type 2 DM correlated with declining olfactory function. However, no differences were observed in olfactory function between patients with type 2 DM with and without comorbidities. These findings provide additional insights into the factors that influence olfactory function in patients with type 2 DM.

摘要

引言

2型糖尿病(DM)患者常出现嗅觉功能障碍;然而,病程与合并症之间的关系仍不清楚。

材料与方法

在棉兰市H. Adam Malik综合医院内分泌与代谢科门诊进行了一项分析性观察研究。该研究纳入了66例符合纳入标准的2型糖尿病患者。数据收集自病历、问卷、常规耳鼻喉科检查以及嗅觉棒测试(<0.05)。

结果

2型糖尿病患者的性别与嗅觉功能之间未观察到显著关系。然而,年龄与嗅觉功能评分之间观察到显著相关性(=0.012),2型糖尿病病程与嗅觉功能评分之间也观察到显著相关性(=0.005)。有合并症和无合并症的2型糖尿病患者的嗅觉功能评分无显著差异。

结论

本研究表明,年龄增长和2型糖尿病病程与嗅觉功能下降相关。然而,有合并症和无合并症的2型糖尿病患者在嗅觉功能方面未观察到差异。这些发现为影响2型糖尿病患者嗅觉功能的因素提供了更多见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90c5/11624848/50b487ef693a/ijo-36-655-g001.jpg

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