Evaluation of Fluoride and Silver Ion Concentrations in e-Silver Diamine Fluoride and Advantage Arrest: An Ion Chromatography and Atomic Absorption Spectrometer Study.

AIMS AND BACKGROUND

Dentin hypersensitivity (DH) is characterized by sharp shooting pain due to exposed dentin, and the most common method for treating this pain is the occlusion of the dentinal tubules with the help of desensitizing agents. E-silver diamine fluoride (e-SDF) (Kids-e-Dental, Mumbai, India) is a commercially available 38% SDF solution in the Indian market. Despite the fact that its application for caries prevention has been proven, the fluoride (Fl) and silver (Ag) ion concentrations of e-SDF for use in treating DH have yet to be standardized. The aim of this study is to determine and compare the Fl and Ag ion concentrations released from two commercially available 38% silver diamine fluoride (SDF) solutions.

MATERIALS AND METHODS

The two most common commercially available 38% SDF solution brands, namely Advantage Arrest and e-SDF were used. Two drops of each of these solutions were taken in three beakers and diluted with distilled water. The Fl ion concentration was evaluated using a calibrated ion-specific electrode. The free Ag ion concentration was assessed using an atomic absorption spectrometry (AAS).

RESULTS

Release of Ag ions shows that on days 1, 2, 5, 6, and 7, concentration (mg/L) was higher in the Advantage Arrest group but is statistically nonsignificant. On days 3 and 4, it is higher in an e-SDF group with a -value of 1.085 and 0.243 and is statistically nonsignificant. Release of Fl ion showed that in comparison to the baseline, it was more with Advantage Arrest on days 2, 4, and 7 with a -value of -3.766, -0.999, and 0.347 and on day 2 was statistically significant. On days 3, 5, and 6 Fl ion release from baseline was more with e-SDF in comparison with Advantage Arrest but statistically insignificant.

CONCLUSION

The AAS analysis as well as the ion chromatography showed that the Ag and Fl ion release respectively on days 1-7 from e-SDF was similar to the one seen in the case of Advantage Arrest.

CLINICAL SIGNIFICANCE

This helps dentists choose among different brands of the same commercially available 38% SDF solutions depending on the cost and availability of the product.

HOW TO CITE THIS ARTICLE

Kamath P, Kamath P, P AN, Evaluation of Fluoride and Silver Ion Concentrations in e-Silver Diamine Fluoride and Advantage Arrest: An Ion Chromatography and Atomic Absorption Spectrometer Study. Int J Clin Pediatr Dent 2024;17(10):1141-1145.