Manrique-Hernandez Edgar Fabian, Ballesteros Goes Esther, Hoyos Madera Kendrys, Bermon Anderson, Hurtado-Ortiz Alexandra, Licht-Ardila Maricel, Nieves-Cuervo Giselly Mayerly
Department of Epidemiology, Fundacion Cardiovascular de Colombia, Santander, Bucaramanga, Colombia.
Department of Oncology, Fundacion Cardiovascular de Colombia, Santander, Bucaramanga, Colombia.
Indian J Palliat Care. 2024 Oct-Dec;30(4):347-352. doi: 10.25259/IJPC_37_2024. Epub 2024 Nov 15.
The objectives of the study are to assess changes in the quality of life amongst breast cancer patients undergoing treatment at a cancer institute in Colombia.
Analytical observational prospective cohort study in patients over 18 years of age diagnosed with breast cancer. Health-related quality of life (HRQoL) was analysed using the EQ-5D-3L questionnaire and a Visual Analogue Scale measured at diagnosis and after a 6-month follow-up. Sociodemographic and clinical factors were analysed using a logistic regression model, with STATA 16 software.
A total of 103 patients met the included criteria and were included in the study, with a median age of 56 years. According to the Tumour, Node, Metastasis classification of cancer stage, the majority of participants (35.92%) were in stage 2 of cancer. Multivariate analysis revealed that changes in HRQoL were significantly associated with age (odds ratio [OR] = 1.06, = 0.001), radiotherapy (OR = 3.56, = 0.038) and moderate anxiety and depression (OR = 5.54, = 0.007).
While the overall quality of life in women with breast cancer showed a slight improvement over the 6 months, older patients and those receiving radiotherapy experienced a greater decline in health perception.
本研究的目的是评估在哥伦比亚一家癌症研究所接受治疗的乳腺癌患者的生活质量变化。
对18岁以上诊断为乳腺癌的患者进行分析性观察前瞻性队列研究。使用EQ-5D-3L问卷和视觉模拟量表在诊断时和6个月随访后分析健康相关生活质量(HRQoL)。使用逻辑回归模型和STATA 16软件分析社会人口统计学和临床因素。
共有103名患者符合纳入标准并被纳入研究,中位年龄为56岁。根据癌症分期的肿瘤、淋巴结、转移分类,大多数参与者(35.92%)处于癌症2期。多变量分析显示,HRQoL的变化与年龄(比值比[OR]=1.06,P=0.001)、放疗(OR=3.56,P=0.038)以及中度焦虑和抑郁(OR=5.54,P=0.007)显著相关。
虽然乳腺癌女性的总体生活质量在6个月内略有改善,但老年患者和接受放疗的患者的健康感知下降更大。