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采用EQ-5D-3L量表对乳腺癌患者配偶的健康相关生活质量进行评估。

Health-related quality of life measured by EQ-5D-3L for the spouses of breast cancer patients.

作者信息

Sun Li-Fei, Huang Sheng, Li Yun-Fen, Yang Zhuang-Qing, Yang Xiao-Juan, Zou Jie-Ya, Wang Xiao-Wen, Nie Jian-Yun

机构信息

Breast Cancer Institute, The Third Affiliated Hospital of Kunming Medical University, Yunnan Cancer Hospital, Kunming, China.

Center for AIDS/STDs Prevention and Control, Yunnan Center for Disease Control and Prevention, Kunming, China.

出版信息

Front Oncol. 2022 Oct 18;12:983704. doi: 10.3389/fonc.2022.983704. eCollection 2022.

Abstract

To explore factors influencing the health-related quality of life of spouses of breast cancer patients and the suitable questionnaires for this purpose. A cross-sectional study was conducted in the Third Affiliated Hospital of Kunming Medical University. The spouses of breast cancer patients were included and evaluated face-to-face interviews. Self-designed demographic characteristics and disease-related questionnaires, the 12-item health survey questionnaire (SF-12), the three-level European five-dimensional health status scale (EQ-5D-3L), and the Social Support Rate Scale (SSRS) were used. The internal consistency reliability measure Cronbach's coefficient, criterion-related validity, construct validity, and sensitivity were used to evaluate the applicability of the EQ-5D-3L. Univariate and multivariate analyses were performed to analyze the factors associated with the health-related quality of life of spouses of breast cancer patients. We investigated a total of 100 spouses of breast cancer patients. Cronbach's α, the internal consistency reliability coefficient, was 0.502. The EQ-5D-3L health utility score was moderately correlated with PCS-12 (r=0.46, p=0.0001) and weakly correlated with MCS-12 (r=0.35, p=0.0001). The EQ-5D-3L health utility score for the spouses of breast cancer patients was 0.870, and the EQ-VAS was 78.3. In multivariate analysis, social support and cognition of the treatment effect were factors that influenced the EQ-5D-3L health utility score. The EQ-5D-3L has good reliability, validity, and sensitivity for measuring the physiological aspects of the health-related quality of life of spouses of BC patients. EQ-5D-3L was considered suitable for this study.

摘要

探讨影响乳腺癌患者配偶健康相关生活质量的因素以及适用于此目的的调查问卷。在昆明医科大学第三附属医院进行了一项横断面研究。纳入乳腺癌患者的配偶并进行面对面访谈评估。使用自行设计的人口统计学特征和疾病相关问卷、12项健康调查问卷(SF - 12)、欧洲五维健康状况三级量表(EQ - 5D - 3L)和社会支持评定量表(SSRS)。采用内部一致性信度测量Cronbach系数、效标关联效度、结构效度和敏感度来评估EQ - 5D - 3L的适用性。进行单因素和多因素分析以分析与乳腺癌患者配偶健康相关生活质量相关的因素。我们共调查了100名乳腺癌患者的配偶。Cronbach's α,即内部一致性信度系数,为0.502。EQ - 5D - 3L健康效用得分与PCS - 12中度相关(r = 0.46,p = 0.0001),与MCS - 12弱相关(r = 0.35,p = 0.0001)。乳腺癌患者配偶的EQ - 5D - 3L健康效用得分为0.870,EQ - VAS为78.3。在多因素分析中,社会支持和对治疗效果的认知是影响EQ - 5D - 3L健康效用得分的因素。EQ - 5D - 3L在测量乳腺癌患者配偶健康相关生活质量的生理方面具有良好的信度、效度和敏感度。EQ - 5D - 3L被认为适用于本研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6bdc/9624509/75740d5cea1a/fonc-12-983704-g001.jpg

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