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十二指肠息肉病:十二指肠型滤泡性淋巴瘤的偶然发现

Duodenal Polyposis: An Incidental Finding of Duodenal-Type Follicular Lymphoma.

作者信息

Hagen Rachael, Tidwell Jasmine, Weng Emily, Goldenberg Steven A, Shaikh Anjiya

机构信息

Internal Medicine, University of Connecticut, Farmington, USA.

Internal Medicine, University of Connecticut Health, Farmington, USA.

出版信息

Cureus. 2024 Nov 7;16(11):e73237. doi: 10.7759/cureus.73237. eCollection 2024 Nov.

DOI:10.7759/cureus.73237
PMID:39650864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11624914/
Abstract

Duodenal-type follicular lymphoma is a newly recognized and rare variant of follicular lymphoma with a good prognosis. Patients may present with non-specific gastrointestinal symptoms, but they are often asymptomatic. Diagnosis usually occurs incidentally during EGD when duodenal polyps are biopsied. We describe the unique case of incidentally found biopsy-proven duodenal-type B cell follicular lymphoma. Secondary involvement by systemic type B-cell lymphoma was excluded. The patient underwent localized radiotherapy, obtaining complete remission six months later, confirmed by pathology. Physicians should be aware of this rare pathology, considering the potential for extra-duodenal systemic B-cell lymphoma.

摘要

十二指肠型滤泡性淋巴瘤是一种新认识的、罕见的滤泡性淋巴瘤变异型,预后良好。患者可能出现非特异性胃肠道症状,但通常无症状。诊断通常在进行内镜下逆行胰胆管造影(EGD)时偶然发现,当时对十二指肠息肉进行活检。我们描述了一例偶然发现的经活检证实的十二指肠型B细胞滤泡性淋巴瘤的独特病例。排除了系统性B细胞淋巴瘤的继发性累及。患者接受了局部放疗,六个月后获得完全缓解,经病理证实。考虑到存在十二指肠外系统性B细胞淋巴瘤的可能性,医生应了解这种罕见的病理情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/7be28642474c/cureus-0016-00000073237-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/0f92c1fac30f/cureus-0016-00000073237-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/e34a968e35ae/cureus-0016-00000073237-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/7be28642474c/cureus-0016-00000073237-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/0f92c1fac30f/cureus-0016-00000073237-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/e34a968e35ae/cureus-0016-00000073237-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d60/11624914/7be28642474c/cureus-0016-00000073237-i03.jpg

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本文引用的文献

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Clinical features and outcomes of duodenal-type follicular lymphoma: A single-center retrospective study.十二指肠型滤泡性淋巴瘤的临床特征与预后:一项单中心回顾性研究
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Successful Clarithromycin Monotherapy in a Patient with Primary Follicular Lymphoma of the Duodenum.十二指肠原发性滤泡性淋巴瘤患者成功接受克拉霉素单药治疗
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