Lodhi Muhammad Farhan, Iqbal Kashif, Bin Yamin Butt Jawad, Muhammad Iqbal Saad, Akber Malik Irfan, Iqbal Faisal, Khalil Hafiz Habib Ur Rehaman
Ophthalmology, Layton Rahmatulla Benevolent Trust (LRBT) Hospital Township, Lahore, PAK.
Ophthalmology, Akhtar Saeed Medical and Dental College, Lahore, PAK.
Cureus. 2024 Nov 7;16(11):e73249. doi: 10.7759/cureus.73249. eCollection 2024 Nov.
Central serous chorioretinopathy (CSC) is a significant cause of vision loss in men aged 20 to 60, characterized by serous detachment of the neurosensory retina from the retinal pigment epithelium (RPE). This study aims to assess the frequency of CSC among patients at a tertiary care center in Pakistan, offering insights into its epidemiology and management within this setting.
A retrospective observational study was conducted at the ophthalmology department of a tertiary care center from January 2019 to December 2023. Patients aged 20 years and above diagnosed with CSC based on clinical examination, fluorescein angiography (FA), and optical coherence tomography (OCT) were included. Data were collected from electronic medical records, encompassing demographic, clinical, and treatment information. Statistical analysis was performed using IBM SPSS Statistics for Windows, version 25 (IBM Corp., Armonk, NY, USA) with descriptive statistics summarizing demographic and clinical characteristics, and chi-square tests and t-tests examining associations between variables.
A total of 83 patients (112 eyes) were studied, with 83.13% being male and 16.87% female. Unilateral CSC was observed in 65.06% of cases, while 34.94% had bilateral involvement. The age group 25-40 years had the highest incidence (57.83%), with Unani medication (39.58%) and systemic hypertension (45.71%) being the most common contributing factors. The most frequent presenting symptom was vision impairment (48.19%).
CSC primarily affects middle-aged men, with observed associations to factors such as traditional Unani medication and systemic hypertension. This study highlights the importance of tailored treatment strategies and the need for further research into CSC's pathogenesis and management in Pakistan.
中心性浆液性脉络膜视网膜病变(CSC)是20至60岁男性视力丧失的重要原因,其特征是神经感觉视网膜与视网膜色素上皮(RPE)发生浆液性脱离。本研究旨在评估巴基斯坦一家三级医疗中心患者中CSC的发病率,为该环境下的流行病学和管理提供见解。
于2019年1月至2023年12月在一家三级医疗中心的眼科进行了一项回顾性观察研究。纳入年龄在20岁及以上、基于临床检查、荧光素血管造影(FA)和光学相干断层扫描(OCT)诊断为CSC的患者。从电子病历中收集数据,包括人口统计学、临床和治疗信息。使用IBM SPSS Statistics for Windows 25版(IBM公司,美国纽约州阿蒙克)进行统计分析,描述性统计总结人口统计学和临床特征,卡方检验和t检验检查变量之间的关联。
共研究了83例患者(112只眼),其中男性占83.13%,女性占16.87%。65.06%的病例为单侧CSC,34.94%为双侧受累。25 - 40岁年龄组发病率最高(57.83%),尤那尼药物治疗(39.58%)和系统性高血压(45.71%)是最常见的促成因素。最常见的症状是视力障碍(48.19%)。
CSC主要影响中年男性,与传统尤那尼药物治疗和系统性高血压等因素有关。本研究强调了定制治疗策略的重要性以及对巴基斯坦CSC发病机制和管理进行进一步研究的必要性。