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绝经后患者腹部子宫切除术和右侧输卵管卵巢切除术后25年罕见巨大卵巢卵泡膜细胞瘤:病例报告及文献综述

A Rare Occurrence of a Huge Ovarian Thecoma in a Menopausal Patient, 25 Years After Abdominal Hysterectomy and Right Salpingo-Oophorectomy: A Case Report and Mini-Review of the Literature.

作者信息

Thanasa Anna, Thanasa Efthymia, Antoniou Ioannis-Rafail, Kontogeorgis Gerasimos, Xydias Emmanouil M, Ziogas Apostolos C, Thanasas Ioannis

机构信息

Department of Health Sciences, Medical School, Aristotle University of Thessaloniki, Thessaloniki, GRC.

Department of Obstetrics and Gynecology, General Hospital of Trikala, Trikala, GRC.

出版信息

Cureus. 2024 Nov 7;16(11):e73258. doi: 10.7759/cureus.73258. eCollection 2024 Nov.

DOI:10.7759/cureus.73258
PMID:39651023
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11625188/
Abstract

Our case involves a 68-year-old postmenopausal patient with a history of total abdominal hysterectomy and right salpingo-oophorectomy performed 25 years ago. The patient presented with chronic pelvic pain for a gynecological examination. Clinically, a large painless pelvic mass was palpable, likely originating from the preserved left ovary. Transvaginal ultrasonography, computed tomography, and magnetic resonance imaging supported the clinical suspicion, and an exploratory laparotomy was subsequently performed. Intraoperatively, a solid, neoplastic, exophytic ovarian tumor was discovered, occupying the entire pelvis. The tumor, along with the ovary and the corresponding fallopian tube, was surgically removed. Histological examination of the specimen confirmed the diagnosis of an ovarian thecoma. Following a four-day hospitalization with an uneventful postoperative course, the patient was discharged from our clinic. Three months later, she reported complete relief from chronic pelvic pain. This report of the case also includes a brief literature review, emphasizing the preoperative diagnostic challenges of this rare clinical entity and the importance of regular gynecological check-ups for women who have undergone total hysterectomy with ovarian preservation.

摘要

我们的病例是一位68岁的绝经后患者,25年前接受了全腹子宫切除术和右侧输卵管卵巢切除术。患者因慢性盆腔疼痛前来进行妇科检查。临床上,可触及一个大的无痛性盆腔肿块,可能起源于保留的左侧卵巢。经阴道超声、计算机断层扫描和磁共振成像均支持临床怀疑,随后进行了剖腹探查术。术中发现一个实性、肿瘤性、外生性卵巢肿瘤,占据了整个盆腔。该肿瘤连同卵巢和相应的输卵管一起被手术切除。标本的组织学检查确诊为卵巢卵泡膜细胞瘤。经过四天的住院治疗,术后过程顺利,患者从我们的诊所出院。三个月后,她报告慢性盆腔疼痛完全缓解。该病例报告还包括简要的文献综述,强调了这种罕见临床实体的术前诊断挑战,以及对接受了保留卵巢的全子宫切除术的女性进行定期妇科检查的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/fc3f0fef61da/cureus-0016-00000073258-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/50cde381886d/cureus-0016-00000073258-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/e864a6248bb0/cureus-0016-00000073258-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/2ebe39549d20/cureus-0016-00000073258-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/48bcd77b6e68/cureus-0016-00000073258-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/9087103d9116/cureus-0016-00000073258-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/1e6882af846a/cureus-0016-00000073258-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/fc3f0fef61da/cureus-0016-00000073258-i07.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/50cde381886d/cureus-0016-00000073258-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/e864a6248bb0/cureus-0016-00000073258-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/2ebe39549d20/cureus-0016-00000073258-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/48bcd77b6e68/cureus-0016-00000073258-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/9087103d9116/cureus-0016-00000073258-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/1e6882af846a/cureus-0016-00000073258-i06.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bcfc/11625188/fc3f0fef61da/cureus-0016-00000073258-i07.jpg

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本文引用的文献

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Application of convolutional neural network for differentiating ovarian thecoma-fibroma and solid ovarian cancer based on MRI.基于 MRI 的卷积神经网络在鉴别卵巢卵泡膜细胞瘤-纤维瘤与卵巢癌实性成分中的应用。
Acta Radiol. 2024 Jul;65(7):860-868. doi: 10.1177/02841851241252951. Epub 2024 May 15.
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Chronic pelvic pain of "unknown origin" in the female.
女性“不明原因”的慢性盆腔疼痛。
Ann Transl Med. 2024 Apr 22;12(2):26. doi: 10.21037/atm-23-1758. Epub 2024 Apr 15.
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The detailed histopathological characteristics of ovarian fibroma compared with thecoma, granulosa cell tumor, and sclerosing stromal tumor.卵巢纤维瘤与卵泡膜细胞瘤、颗粒细胞瘤及硬化性间质瘤相比的详细组织病理学特征。
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Relevance of Molecular Pathology for the Diagnosis of Sex Cord-Stromal Tumors of the Ovary: A Narrative Review.分子病理学在卵巢性索间质肿瘤诊断中的相关性:一篇叙述性综述
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